猪瘟病毒持续感染与预防控制

Persistent Infection and Prevention Control of Classical Swine Fever Virus

猪瘟是由猪瘟病毒感染引发的一种病毒性传染性疾病,该种疾病是国家一类重特大传染性疾病,在自然条件下猪瘟病毒持续感染,通常和猪群免疫能力较低有密切联系。在临床上持续感染猪瘟的猪能持续带毒,并会持续向外排出病毒污染周围环境,另外带毒的种猪也可以通过母猪胎盘或公猪精液传播给仔猪,造成仔猪出现先天性的免疫耐受,导致疫苗免疫失败。该文主要分析猪瘟疫苗免疫失败原因,分析猪瘟病毒持续感染与疫苗免疫失败之间的联系,提出相应的预防控制措施。

Classical swine fever is a viral disease caused by the infection of classical swine fever virus.The disease is a major infectious disease in the country.Under natural conditions,the infectious disease virus continues to infect,is usually associated with lower immunity in the herd.Pigs that are continuously infected with classical swine fever can carry the virus and continuously expel the virus to pollute the surrounding environment.In addition,infected breeding pigs can also be transmitted to piglets through sows'placenta or boar semen,the result is that the piglets have innate immune tolerance,which leads to the failure of vaccine immunity.In this paper,the reasons of classical swine fever virus immune failure and the relationship between classical swine fever virus persistent infection and Vaccine Immune failure were analyzed,and the corresponding preventive measures were put forward.