摘要
AA9家族的裂解性多糖单加氧酶(lytic polysaccharide monooxygenase,LPMO)广泛存在于真菌中,由于其能作用于木质纤维素的结晶多糖,从而使其在生物转化生物质方面发挥重要的作用。本文首先综述了AA9家族LPMO的结构特点、催化机制、结构与功能之间的关系,其次阐述了AA9家族LPMO的微生物表达与调控,最后简单介绍了AA9家族LPMO在转化木质纤维素中的应用。
The lytic polysaccharide monooxygenase(LPMO)of AA9 is widely distributed in fungi and plays an important role in the bioconversion of biomass because it can degrade crystalline polysaccharide of lignocellulose.The detailed information of the structural features,catalytic mechanism,structure and function and microbial expression and regulation of AA9 LPMO is summarized.Finally,the applications of AA9 LPMO in the conversion of lignocellulose are also discussed.
作者
郭宵
安亚静
柴成程
蒋露莹
路福平
刘夫锋
戴玉杰
GUO Xiao;AN Ya-Jing;CHAI Cheng-Cheng;JIANG Lu-Ying;LU Fu-Ping;LIU Fu-Feng;DAI Yu-Jie(Key Laboratory of Industrial Fermentation Microbiology,Ministry of Education,Tianjin Key Laboratory of Industrial Microbiology,National Engineering Laboratory for Industrial Enzymes,College of Biotechnology,Tianjin University of Science&Technology,Tianjin 300457,China)
出处
《微生物学通报》
CAS
CSCD
北大核心
2020年第7期2309-2320,共12页
Microbiology China
基金
国家重点研发计划(2018YFA0901700)。
关键词
木质纤维素
生物转化
裂解性多糖单加氧酶
构效关系
微生物表达
Lignocellulose
Bioconversion
Lytic polysaccharide monooxygenase
Structure-function relationship
Microbial expression
