摘要
Single-cell transcriptomic analysis has provided an unprecedented avenue for the identification of neuronal subtypes that are affected in neurological diseases.However,this strategy is largely hindered by the difficulty of collecting fresh samples of adult human brain.Instead,postmortem brain tissue from both normal and diseased human subjects is more accessible.
基金
supported by Grants from the National Natural Science Foundation of China (31490591)
the National Key R&D Program of China (2017YFA0700500)
a Frontier Key Project of the Chinese Academy of Sciences (QYZDJ-SSWSMC025)
a Shanghai Municipal Science and Technology Major Project,China (2018SHZDZX05)。