不同手术方法治疗子宫肌瘤对术后患者内分泌状态影响的研究

Study on the Effect of Different Surgical Methods on Uterine Fibroids on the Endocrine Status of Postoperative Patients

目的探讨临床对子宫肌瘤患者应用不同手术方法治疗的内分泌影响。方法选取2018年8月—2019年9月我院收治的120例子宫肌瘤患者为临床对象,按照患者意愿和肌瘤具体情况进行分组,分为A组(40例)、B组(40例)、C组(40例)。A组患者接受子宫肌瘤剥除术的方法,B组患者接受子宫全切除术的方法,C组患者接受子宫部分切除术的方法。评估和对比三组患者在不同手术方法治疗下对术后内分泌状态的影响。结果A组患者在手术前后的血清激素水平(除FSH外),对比差异无统计学意义(P>0.05);术后6个月,B、C组两组患者的E2水平在术后下降,与术前比较差异具有统计学意义(P<0.05);年龄>40岁的患者,B、C组E2水平低于术前(P<0.05)。结论不同手术方法治疗子宫肌瘤对术后患者内分泌状态的影响不同,且年龄不同内分泌的影响差异也不同。但临床对子宫肌瘤患者应用子宫肌瘤剥除术治疗能够保留子宫,且手术创伤面积小,损伤小,血管供血少,恢复时间短,心理影响小,不会影响盆底功能。

Objective To explore the endocrine effects of different surgical methods in the treatment of patients with uterine fibroids.Methods From August 2018 to September 2019,120 cases of hysteromyoma patients admitted to our hospital were selected as clinical objects,and they were divided into groups according to the wishes of patients and the specific conditions of the leiomyoma.They were divided into groups A(40 cases),group B(40 cases),group C(40 cases).Patients in group A received hysteromyomectomy,patients in group B received total hysterectomy,and patients in group C received partial hysterectomy.To evaluate and compare the effects of the three groups of patients under different surgical methods on postoperative endocrine status.Results The serum hormone levels(except FSH)of patients in group A before and after operation were not significantly different(P>0.05);6 months after operation,the E2 levels of patients in groups B and C decreased significantly after surgery,compared with The preoperative comparison was statistically significant(P<0.05);for patients>40 years of age,the E2 levels in groups B and C were lower than before surgery(P<0.05).Conclusion Different surgical methods for the treatment of uterine fibroids have different effects on the endocrine status of postoperative patients,and the effects of endocrine vary with age.However,the clinical application of uterine myomectomy in patients with uterine fibroids can preserve the uterus,and the surgical area is small,the damage is small,the blood supply to the blood vessels is small,the recovery time is short,the psychological impact is small,and the pelvic floor function will not be affected.