超声和DSA引导下胸椎背根神经节脉冲射频术联合神经妥乐平治疗45例带状疱疹神经痛的临床价值

Clinical value of pulsed radiofrequency ablation of thoracic dorsal root ganglion guided by ultrasound and DSA combined with neurotropin in the treatment of 45 patients with herpes zoster neuralgia

目的 :探究超声和数字减影血管造影(DSA)引导下胸椎背根神经节脉冲射频术结合注射神经妥乐平治疗带状疱疹神经痛的临床价值。方法 :选取90例带状疱疹神经痛患者随机分为两组对照组(n=45,行神经妥乐平注射治疗)和观察组(n=45,采用超声和DSA引导下胸椎背根神经节脉冲射频联合神经妥乐平注射治疗),对比两组治疗后1 d、1周、1个月、3个月时VAS评分变化,记录治疗期间并发症情况。结果 :治疗后两组患者VAS评分明显改善,观察组术后各时间点VAS评分低于对照组(P<0.05);两组患者均无严重并发症情况,轻度药物致并发症发生率差异无统计学意义(P>0.05)。结论 :超声和DSA引导下胸椎背根神经节脉冲射频联合神经妥乐平治疗带状疱疹神经痛可更好缓解疼痛,且安全性满足要求。

Objective: To investigate the clinical value of ultrasound and digital subtraction angiography(DSA)-guided thoracic dorsal root ganglion pulsed radiofrequency combined with the injection of neurotropin in the treatment of herpes zoster neuralgia. Methods: Ninety patients with herpes zoster neuralgia were randomly divided into a control group(n=45) and an observation group(n=45). The changes of VAS scores at 1 day, 1 week, 1 month and 3 months after treatment were compared between the two groups. Results: After treatment, the VAS scores were significantly improved in the two groups and the VAS scores were lower in the observation group than the control group(P<0.05). There were no significant differences between the two groups in the incidence of minor drug-induced complications(P>0.05). Conclusion: Pulsed radiofrequency of thoracic dorsal root ganglion guided by ultrasound and DSA combined with neurotropin can better relieve pain with satisfactory safety.