低频神经肌肉电刺激联合前列地尔对30例急性缺血性脑卒中患者下肢运动功能的影响

Effect of low frequency neuromuscular electrical stimulation combined with alprostadil on lower extremity motor function in 30 patients with acute ischemic stroke

目的 :观察低频神经肌肉电刺激联合前列地尔对急性缺血性脑卒中患者下肢运动功能的影响。方法 :双盲选取90例急性缺血性脑卒中并伴有下肢运动功能障碍的患者随机分为3组各30例,其中常规治疗组给予常规康复治疗,低频NMES组给予常规康复治疗+低频NMES治疗,联合治疗组在低频神经肌肉电刺激(neuromuscular electrical stimulation, NMES)组治疗基础上联合前列地尔治疗,分别在治疗前与治疗6周后采用简易下肢Fugl-Meyer量表(FMA)、改良Barthel指数评分(MBI)和Berg平衡量表(BBS)评定患者的下肢运动能力。结果 :3组患者的各项指标在治疗前评分差异无统计学意义。治疗6周后,联合治疗组的3项指标评分升高较其他两组疗效更显著(P<0.05)。结论 :在常规康复治疗基础上加用低频NMES联合前列地尔可有效改善急性缺血性脑卒中患者的下肢运动功能。

Objective: To observe the effect of low frequency neuromuscular electrical stimulation combined with alprostadil on motor function of lower limbs in patients with acute ischemic stroke. Methods: Ninety patients with acute ischemic stroke and lower extremity dyskinesia were randomly divided into 3 groups with 30 cases each. The conventional treatment group was treated with conventional rehabilitation therapy, the low-frequency NMES group with conventional rehabilitation therapy plus low-frequency NMES therapy, and the combined treatment group with alprostadil combined with NMES therapy. The lower extremity dyskinesia before treatment and 6 weeks after were evaluated by FMA, MBI and BBS. Results: There were no significant differences among the three groups in the scores before treatment. The rise of the scores was more significant in the combined treatment group than the other two groups 6 weeks after treatment(P<0.05). Conclusion: The combination of lowfrequency NMES and alprostadil can effectively improve the motor function of lower limbs in patients with acute ischemic stroke.