基于CiteSpace Ⅴ软件的患者报告结局文献计量学分析

Bibliometric Analysis of Patient-reported Outcomes Using CiteSpace Ⅴ

背景 随着“以患者为中心”的医学模式的转变,患者在医疗服务中的角色和地位越来越重要,患者对自身健康相关信息的报告在识别/监测症状、评估治疗效果以及在医患共享决策等方面体现出其独特的临床价值。然而,我国患者报告结局(PROs)相关研究还处于起步阶段,尚缺乏基于PROs的文献计量学研究。目的 了解国际PROs研究成果及研究热点,为我国开展相关研究提供借鉴与参考。方法 基于“Web of Science核心合集”数据库,运用文献计量学分析方法和CiteSpaceⅤ软件对PROs相关研究的年度变化、主要国家/地区、机构、期刊、关键词及研究热点进行可视化分析,检索时间为建库至2019年8月。结果 通过检索最终获得3 288篇相关文献;近年来PROs相关研究报道逐年增多,美国发文量最多,为1 815篇(55.20%);发文量最多的研究机构为美国西北大学;相关研究共发表在822种出版物上,以Quality of Life Research发文量最多(148篇);中心性排名靠前的关键词为生活质量(quality of life)、患者报告结局(patient-reported outcome)、量表(questionnaire)、检验(validation)、影响(impact)、信度(reliablity)等,研究热点以PROs、健康相关生活质量、患者报告结局测量、临床应用研究等为主。结论 以美国为首的发达国家在PROs相关研究占有领先地位,我国在该领域的高质量研究还很少,建议国内学者基于我国国情,结合我国传统中医药特色,完善PROs相关研究的发展。

Background The transformation of the traditional medical model to patient-centered medical model indicates that the role of patients are becoming increasingly important in healthcare industry.And patient-reported health information demonstrates distinctive significance in identifying/monitoring symptoms,evaluating treatment effect and sharing decision-making.However,the research on patient-reported outcomes(PROs)is still in its infancy in China,and bibliometric studies based on PROs are still lacking.Objective To evaluate the research results and hotspots about PROs from a global perspective,to provide references for relevant studies in China.Methods Studies about PROs were searched from the database of Web of Science Core Collection from inception to August 2019.Bibliometric analysis and CiteSpaceⅤwere used to conduct a visualization analysis of the enrolled studies in terms of changes in annual publication number,major author countries/regions and institutions,publishing journals,keywords and research hotspots.Results A total of 3288 studies were enrolled.The annual number of these published studies showed a recent increasing trend.The country publishing the most studies was the United States,accounting for 55.20%(1815/3288)of the total.The institution with the largest number of papers published was Northwestern University.The publications in which the studies were published numbered 822,among which Quality of Life Research published the most(n=148).The top 6 keywords with highest centrality value were"quality of life""patient-reported outcomes""questionnaire""validation""impact""reliability".The major hotspots were PROs,health-related quality of life,measurement of PROs,and clinical application of PROs.Conclusion Developed countries,led by the United States,take the lead in this field,and there are few high-quality studies in this field in China.Therefore,to improve the development of PROs related studies in China,scholars are suggested to put efforts on domestic PROs related development as well as features of traditional Chinese medicine.