不同介入方案治疗急性下肢静脉血栓的临床效果与安全性比较

Comparison of clinical effects and safety of different interventional schemes in the treatment of acute lower extremity venous thrombosis

目的探讨不同介入方案治疗急性下肢静脉血栓(DVT)的临床效果与安全性。方法选取我院2015年1月~2019年12月介入科收治的急性DVT患者54例作为研究对象,按照治疗方式的不同分为研究组27例和对照组27例。研究组采用血管腔内综合治疗,对照组采用导管介导溶栓治疗,比较两组患者疗效评价、治疗前后膝上、下15 cm与患肢周径差、治疗前后皮肤肿胀张力、静脉通畅率、住院时间和并发症发生情况。结果经治疗后研究组患者膝上、下15 cm与患肢周径差均短于对照组(P<0.05);经治疗后研究组患者皮肤肿胀张力恢复程度显著优于对照组(P<0.05);经治疗后研究组患者静脉通畅率显著高于对照组(P<0.05);研究组治疗有效率显著高于对照组(P<0.05);研究组患者住院时间明显少于对照组,且其并发症发生率显著低于对照组(P<0.05)。结论血管腔内综合介入治疗能够有效改善患者下肢症状,提高DVT恢复情况,降低并发症的发生,从而有效提高患者生活质量,为临床治疗DVT提供重要参考。

Objective To explore the clinical effect and safety of different interventional schemes in the treatment of acute lower extremity deep venous thrombosis(DVT).Methods Fifty-four patients with acute DVT admitted to the intervention therapy department from January 2015 to December 2019 in our hospital were selected as the research object,and were divided into a research group 27 cases and a control group 27 cases according to different treatment methods.The study group received intravascular combined therapy,and the control group received catheter-mediated thrombolysis therapy.The efficacy evaluation,the circumference difference between the healthy and affected limbs at 15 cm above and below the knee before and after treatment,the skin swelling tension before and after treatment,the venous patency rate,the length of hospital stay and the occurrence of complications between the two groups were compared.Results After treatment,the circumference difference between the healthy and affected limbs at 15 cm above and below the knee in the study group was shorter than that of the control group(P<0.05).After treatment,the recovery of skin swelling and tension in the study group was significantly better than that of the control group(P<0.05).The venous patency rate of the study group was significantly higher than that of the control group(P<0.05).The treatment efficiency of the study group was significantly higher than that of the control group(P<0.05).The hospital stay of the study group was significantly shorter than that of the control group,and the incidence of complications in the study group was significantly lower than that of the control group(P<0.05).Conclusion Intravascular combined intervention therapy can effectively improve patients'lower extremity symptoms,improve DVT recovery and reduce the occurrence of complications,thus improving the patient's quality of life and providing an important reference for clinical treatment of DVT.