血清胆红素与尿酸检验用于冠心病临床诊断的分析

Analysis of serum bilirubin and uric acid testsin clinical diagnosis of coronary heart disease

目的:探讨血清胆红素与尿酸检验用于冠心病临床诊断的价值。方法:选取冠心病患者100例作为研究组,同期健康体检者100例作为对照组。对比两组血清胆红素与尿酸检验结果。结果:研究组总胆红素、直接胆红素及间接胆红素水平均低于对照组,尿酸水平高于对照组,差异有统计学意义(P<0.05)。随着冠状动脉狭窄程度增加,总胆红素、直接胆红素、间接胆红素水平逐渐降低,尿酸水平逐渐升高,差异有统计学意义(P<0.05)。不同类型冠心病比较,UAP组尿酸及胆红素水平高于SAP组,NQM1组、QM1组胆红素及尿酸水平明显高于SAP组、UAP组,差异均有统计学意义(P<0.05)。结论:血清胆红素与尿酸检验用于冠心病临床诊断价值高,可以辅助临床医生进行冠心病的诊断及疾病严重程度评估,帮助评价治疗效果。

Objective:To explore the value of serum bilirubin and uric acid tests in clinical diagnosis of coronary heart disease.Methods:100 patients with coronary heart disease were selected as study group and 100 health people who underwent physical examination in the same period were selected as control group.The results of serum bilirubin and uric acid tests were compared between the two groups.Results:The levels of total bilirubin,direct bilirubin and indirect bilirubin in the study group were lower than those in the control group,and the level of uric acid was higher than that of control group,the differences were statistically significant(P<0.05).With the degree of coronary artery stenosis increased,the levels of total bilirubin,direct bilirubin and indirect bilirubin decreased,however the levels of uric acid increased,the differences were statistically significant(P<0.05).Compared with different types of coronary heart disease,UAP group had higher levels of uric acid and bilirubin than SAP group,the levels of bilirubin and uric acid in NQM1 and QM1 group were higher than those in SAP and UAP group,the differences were statistically significant(P<0.05).Conclusion:Serum bilirubin and uric acid tests have high clinical value in diagnosing coronary heart disease,it helps clinicians to diagnose coronary heart disease and assesses the severity of the condition,it also helps to evaluate the effectiveness of treatment.