补肾活血中药辅助以西药治疗排卵障碍性不孕临床效果

Effect of tonifying kidney and activating blood recipe combined with western medicine for treating infertile patients with ovulation disorder

目的:观察补肾活血中药辅以西药治疗排卵障碍性不孕不育临床效果。方法:选取2016年7月-2018年11月本院收治的排卵障碍性不孕不育患者118例,按入院顺序分组,西医组给予常规枸橼酸氯米芬胶囊治疗,中西医组在西医组治疗基础上给予补肾活血中药治疗,比较两组临床疗效。结果:治疗后中西医组总有效率(93.2%)和基础体温(BBT)正常率(81.4%)高于对照组(79.7%、52.5%),黄体生成素、卵泡激素、孕酮和雌二醇水平高于西医组,子宫内膜厚度(9.8±1.8 mm)、卵泡直径(18.7±1.4mm)长于西医组,优势卵泡数量(1.4±1.3个)少于对照组,排卵率(91.4%)和妊娠率(54.2%)高于对照组(均P<0.05)。结论:补肾活血中药治疗排卵障碍性不孕不育疗效显著,可提高患者BBT正常率,改善性激素水平,改善卵泡直径和优势卵泡数量。

Objective:To study the effect of tonifying kidney and activating blood recipe combined with western medicine for treating infertile patients with ovulation disorder.Methods:118 infertility patients with ovulation disorder were divided into two groups according to the order of admission from July 2016 to November 2018.The patients in the control group were treated with conventional clomiphene citrate capsule,and patients in the observation group were treated with traditional Chinese medicine of tonifying kidney and activating blood combined with clomiphene citrate capsule.The clinical curative effect of patients was compared between the two groups.Results:After treatment,the total effective rate and rate of normal BBT of patients in the observation group were 93.2%and 81.4%,which were significant higher than those(79.7%and 52.5%)of women in the control group.The levels of luteinizing hormone,follicle hormone,progesterone and estradiol of patients in the observation group were significant higher than those of patients in the control group.The endometrial thickness and follicle diameter of patients in the observation group,the ovulation rate and,pregnancy rate were 9.8±1.8 mm,18.7±1.4 mm,91.4%,and 54.2%,which were significant higher than those of patients in the control group,but the dominant follicle number of patients in the observation group was 1.4±1.3,which was significant less(all P<0.05).Conclusion:Traditional Chinese medicine of tonifying kidney and activating blood for treating can improve the normal BBT rate,increase the level of sex hormones,and improve the diameter of follicles and the number of dominant follicles.