子痫前期预测指标及症状前治疗的研究进展

Research progress of prediction index and presymptomatic treatment of preeclampsia

子痫前期(PPE)是妊娠特有的全身性疾病,影响3%~5%的孕妇,在发展中国家孕妇PE的发病率高达10%,基本病理变化是全身小血管痉挛,内皮损伤和局部缺血。然而PE临床干预停滞于症状出现后的被动处理,往往预后不良,因此早期诊断PE的标志物研究以及PE症状前预防研究成为热点。本文从早期预测诊断子痫前期的标志物进展及子痫前期症状前治疗方法两个方面进行综述,以期实现对子痫前期的早期诊断,早期预防,早期治疗。

Preeclampsia(PE)is a specific systemic disease of pregnancy,which affects 35%of pregnant women.The incidence of PE of pregnant women in developing countries is as high as 10%.The basic pathological changes of PE are systemic small vasospasm,vascular endothelial damage,and local ischemia.However,the clinical treatment of PE is stagnation in the passive treatment after the onset of PE,and the prognosis is often poor.Therefore,the research on the early diagnosis markers of PE and prevent measurement before PE onset have become hot spots.This paper reviews the progress of early prediction and diagnosis of PE markers and the treatment methods before PE onset,so as to realize the early diagnosis,early prevention,and early treatment of PE.