腹腔镜直肠癌根治术对老年结直肠癌患者的胃肠功能、胃动素和胃泌素的影响研究

Effects of Laparoscopic Radical Rectal Cancer Surgery on Gastrointestinal Function,Motilin and Gastrin in Elderly Patients with Colorectal Cancer

目的分析腹腔镜直肠癌根治术对老年结直肠癌患者的胃肠功能、胃动素和胃泌素的影响。方法方便选取2016年3月—2019年3月在该院接受手术治疗的109例结直肠癌患者为研究对象。按照接受手术方法的不同,分为治疗组和对照组,两组分别开展腹腔镜直肠癌根治术和开腹直肠癌根治术,对比两组患者围手术期相关临床指标、术后疼痛评分、并发症发生情况;手术前后帮助患者进行胃动素和胃泌素检测和对比。结果治疗组手术时长(180.16±23.16)min,切口长度(5.84±2.11)cm、出血量(77.93±29.15)mL、术后排气时间(60.34±5.88)h、进食时间(55.12±3.54)h、住院时间(11.43±3.12)d,对照组手术时长(141.37±28.19)min,切口长度(18.73±4.62)cm、出血量(166.31±43.16)mL、术后排气时间(84.86±15.43)h、进食时间(103.54±9.15)h、住院时间(17.83±5.42)d;两组比较差异有统计学意义(t=7.856、18.793、12.549、11.001、36.559、7.572,P<0.05)。治疗组术后胃动素(325.64±28.53)pg/mL,胃泌素(136.71±15.74)pg/mL,对照组胃动素(279.16±18.34)pg/mL,胃泌素(118.73±18.19)pg/mL,组间数据对比差异有统计学意义(t=121.892、89.791,P<0.05)。结论老年结直肠癌患者开展腹腔镜直肠癌根治术效果佳、创伤低、并发症少,对胃动素、胃泌素的影响更小,利于老年患者术后胃肠功能及早恢复。

Objective To analyze the effects of laparoscopic radical rectal cancer surgery on gastrointestinal function,motilin and gastrin in elderly patients with colorectal cancer.Methods A total of 109 patients with colorectal cancer who underwent surgical treatment in the hospital from March 2016 to March 2019 were included in the study.According to the different surgical methods,they were divided into a treatment group and a control group.The two groups underwent laparoscopic radical rectal cancer surgery and open radical rectal cancer radical surgery.The clinical indicators,postoperative pain scores,and complications incidence of symptoms;help patients to detect and compare motilin and gastrin before and after surgery were compared between the two groups.Results The length of surgery in the treatment group(180.16±23.16)min,the length of the incision(5.84±2.11)cm,the amount of bleeding(77.93±9.15)mL,the postoperative exhaust time(60.34±5.88)h,the time to eat(55.12±3.54)h,and the length of hospitalization(11.43±3.12)d,control group surgery time(141.37±28.19)min,incision length(18.73±4.62)cm,bleeding volume(166.31±43.16)mL,postoperative exhaust time(84.86±15.43)h,eating time(103.54±9.15)h,hospitalization time(17.83±5.42)d;the difference between the two groups was statistically significant(t=7.856,18.793,12.549,11.001,36.559,7.572,P<0.05).Motilin(325.64±28.53)pg/mL,gastrin(136.71±15.74)pg/mL in the treatment group after treatment,motilin(279.16±18.34)pg/mL,and gastrin(118.73±18.19)pg/mL in the control group.There was a statistically significant difference in data comparison between the groups(t=121.892,89.791,P<0.05).Conclusion Laparoscopic radical resection of colorectal cancer in elderly patients has good effect,low trauma and fewer complications,and has less effect on motilin and gastrin,which is beneficial to early recovery of gastrointestinal function in elderly patients.