黏液脓性宫颈炎微生物的培养及药敏测定分析

Culture and Drug Sensitivity Analysis of Mucus-concentrated Cervicitis

目的黏液脓性宫颈炎(Mucopurulent Cervicitis,MPC)微生物的培养及药敏测定分析。方法方便选择2017年11月—2019年4月期间该院收治的64例黏液脓性宫颈炎患者且设为研究组,另外选择64名健康体检者且设为对照组,取阴道分泌物进行检测,观察微生物培养及药敏试验结果。结果研究组细菌阳性率67.1%,假丝酵母菌阳性率14.1%,支原体阳性率42.1%,阴性率35.9%,对照组分别为73.4%、10.9%、20.3%、64.1%,细菌阳性率、假丝酵母菌阳性率差异无统计学意义(χ^2=0.949、0.468,P=0.329、0.493),而支原体阳性率及阴性率差异有统计学意义(χ^2=11.069、15.904,P=0.000、0.000)。研究组细菌培养为革兰阳性菌与革兰阴性菌;药敏试验显示包括大环内酯类、青霉素、喹诺酮、红霉素、多肽类、头孢类以及少数氨基糖胺类抗生素和β-内酰胺类;分析发现,黏液脓性宫颈炎可能和人流及孕产史、性伴侣>2个、妇科炎症史、合并症等有关,与卫生习惯、文化程度等无关。结论引起黏液脓性宫颈炎的原因较多,大多数和支原体感染存在关联,临床治疗时,应该根据微生物培养及药敏试验结果,制定合理的治疗方案。

Objective Culture and drug sensitivity analysis of mucopurulent cervicitis(MPC)microorganisms.Methods Sixty-four patients with mucinous cervicitis treated in the hospital between November 2017 and April 2019 were convenienty selected as the study group,and another 64 healthy subjects were selected as the control group.Vaginal secretions were taken for testing.Observe the results of microbial culture and drug sensitivity tests.Results the positive rate of bacteria in the study group was 67.1%,the positive rate of Candida was 14.1%,the positive rate of Mycoplasma was 42.1%,and the negative rate was 35.9%.The control group was 73.4%,10.9%,20.3%,and 64.1%,respectively.There was no statistical significant difference in the rate and positive rate of Candida(χ^2=0.949,0.468,P=0.329,0.493),while the positive rate and negative rate of Mycoplasma were statistically significant different(χ^2=11.069,15.904,P=0.000,0.000).The bacterial culture of the research group was Gram-positive and Gram-negative bacteria;drug sensitivity tests showed that they included macrolides,penicillin,quinolone,erythromycin,peptides,cephalosporins,and a few aminoglycosamine antibiotics andβ-lactams;The analysis found that mucoconstrictive cervicitis may be related to abortion and motherhood history,sexual partners>2,history of gynecological inflammation,comorbidities,etc.,and has nothing to do with health habits,education and so on.Conclusion There are many causes of mucoid cervicitis,most of which are related to mycoplasma infection.In clinical treatment,a reasonable treatment plan should be formulated based on the results of microbial culture and drug sensitivity tests.