艾滋病患者机会性感染的临床特点及相关性影响评价

Evaluation of Clinical Characteristics and Related Impact of Opportunistic Infections in AIDS Patients

目的分析(AIDS)艾滋病患者合并机会性感染的临床特征,以此为基础进一步分析干预后情况。方法选择该地区于2008年1—2018年12月间收治的800例(AIDS)艾滋病住院患者合并机会性感染资料,分析资料中有关合并机会性感染的内容,探究相关差异以及预后效果。结果(AIDS)艾滋病患者病死率相对较高,且病死率和患者出现的合并机会性感染有着直接关系,该研究细菌性肺炎432(54.0%)例、巨细胞病毒性肺炎27(3.3%)例、弓形虫脑病25(3.1%)例、隐球菌脑炎56(7.0%)例、细菌性腹膜炎21(2.6%)例、细菌性脑膜炎49(6.1%)例、慢性单纯疱疹32(4.0%)例、复发性败血症31(3.8%)例、播散性真菌病41(5.1%)例、口腔念珠菌病213(26.6%)例、肺结核246(30.7%)例、肺外结核病124(15.5%)例、肺孢子菌肺炎217(27.1%)例、慢性肠炎42(5.2%)例。结论(AIDS)艾滋病患者合并性感染有着特殊的临床特征,病情整体呈现出复杂、危重等特征,多数患者存在多种感染或者多部位感染的情况,预后效果差,(AIDS)艾滋病患者合并机会性感染也是导致死亡的重要原因之一。

Objective To analyze the clinical characteristics of AIDS patients with opportunistic infections,and to further analyze the situation after intervention.Methods The data of 800 AIDS inpatients with opportunistic infections admitted to a certain area from January 2008 to December 2018 were selected,and the contents of the data were analyzed to explore the relevant differences and prognostic effects.Results(AIDS)The mortality rate of AIDS patients is relatively high,and the mortality rate is directly related to the combined opportunistic infections.In this study,432(54.0%)cases of bacterial pneumonia,27(3.3%)cases of cytomegalovirus pneumonia,25(3.1%)cases of toxoplasmosis encephalopathy;56(7.0%)cases of cryptococcal encephalitis,and 21(2.6%)cases(bacterial peritonitis);bacterial meningitis 49(6.1%)cases,chronic herpes simplex 32(4.0%)cases,recurrent sepsis 31(3.8%)cases;disseminated fungal disease 41(5.1%)cases,oral rosary 213(26.6%)cases of bacterial diseases,246(30.7%)cases of pulmonary tuberculosis;124(15.5%)cases of extrapulmonary tuberculosis,217(27.1%)cases of pneumocystis pneumonia,and 42(5.2%)cases of chronic enteritis.Conclusion(AIDS)AIDS patients with co-infection have special clinical characteristics,the overall situation presents complex,critical and other characteristics.Most patients have multiple infections or multi-site infections,and the prognosis is poor.(AIDS)AIDS patients with opportunistic infections is also one of the important causes of death.