妊娠晚期女性B族链球菌携带情况及对母婴妊娠结局的影响分析

Carrying Status of Group B Streptococcus in the Third Trimester of Pregnancy and Its Effect on Maternal and Infant Pregnancy Outcomes

目的研究妊娠晚期女性B族链球菌携带情况及对母婴妊娠结局的影响。方法研究对象为2017年6月—2019年6月该院门诊产检并于该院分娩的200例妊娠晚期孕妇,所有孕妇均进行B族链球菌检测,分析B族链球菌携带情况及对母婴妊娠结局产生的影响。结果200例妊娠晚期孕妇中,B族链球菌阴性率、阳性率分别为87.50%(175/200)、12.50%(25/200)。对比阴性孕妇,阳性孕妇发生宫内感染、宫内窘迫的几率更高,分别为28.00%、48.00%,差异有统计学意义(χ^2=12.528、19.459,P<0.05);阳性孕妇与阴性孕妇发生早产、胎膜早破的几率差异无统计学意义(P>0.05)。对比阴性孕妇新生儿,阳性孕妇新生儿发生肺炎、上呼吸道感染的几率更高,分别为28.00%、32.00%,差异有统计学意义(χ^2=21.731、16.824,P<0.05)。结论携带B族链球菌会增大妊娠晚期孕妇发生宫内感染、宫内窘迫的几率,还会增加新生儿肺炎、上呼吸道感染发生率,因此应重视筛查B族链球菌,进而改善母婴妊娠结局。

Objective To study the carrying status of group B streptococcus in the third trimester of pregnancy and its effect on the pregnancy outcome of mother and infant.Methods The research subjects were 200 pregnant women in late pregnancy who were delivered in the hospital from June 2017 to June 2019.All pregnant women were tested for Group B streptococcus.To analyze the carrying status of group B streptococci and its impact on the outcome of maternal and infant pregnancy.Results Among 200 pregnant women in the third trimester,the negative and positive rates of group B streptococcus were 87.50%(175/200)and 12.50%(25/200),respectively.Compared with negative pregnant women,positive pregnant women had a higher probability of intrauterine infection and intrauterine distress,which were 28.00%and 48.00%,respectively,the difference was not statistically significant(χ^2=12.528,19.459,P<0.05);There was no statistically significant difference in the probability of premature delivery and premature rupture of membranes(P>0.05).Compared with negative pregnant women,positive pregnant women had higher rates of pneumonia and upper respiratory tract infections,which were 28.00%and 32.00%,the difference was statistically significant(χ^2=21.731,16.824,P<0.05).Conclusion Carrying group B streptococci can increase the chance of intrauterine infection and intrauterine distress in pregnant women during the third trimester,and also increase the incidence of neonatal pneumonia and upper respiratory tract infections,therefore,attention should be paid to the screening of group B streptococci to further improve maternal and infant pregnancy outcomes.