摘要
肺动脉高压(PAH)与心律失常具有明确相关性,其中以室上性心动过速(SVT)多见,且有其独特的电生理特性。心律失常发病机制主要包括心肌解剖重构、电重构以及自主神经功能异常。PAH合并心律失常的治疗手段趋于多元化,主要包括药物、介入与外科治疗。右房扩大、高龄以及P波/QTc离散度、心率变异性(HRV)与心率震荡(HRT)异常等是PAH患者发生心律失常的危险因素。
Pulmonary arterial hypertension(PAH)has a certain correlation with arrhythmia,supraventricular tachycardia(SVT)is more common,and has its unique electrophysiological characteristics.The pathogenesis of arrhythmia mainly includes myocardial anatomical remodeling,electrical remodeling and autonomic nerve dysfunction.PAH with arrhythmia tend to be treated in a variety of ways,including drugs,interventional therapy and surgery.Right atrial enlargement,the elderly,and abnormal P wave/QTc dispersion,heart rate variability(HRV)and heart rate turbulence(HRT)are risk factors for PAH patients with arrhythmia.
作者
饶洋洋
周红梅
李艺
陶凉
RAO Yangyang;ZHOU Hongmei;LI Yi;TAO Liang(Department of Cardiothoracic Surgery,Wuhan Asian Heart Hospital Affiliated to Wuhan Universityof Science and Technology,Wuhan,430022,China;Department of Pulmonary Hypertension Center,Wuhan Asian Heart Hospital Affiliated to Wuhan University of Science and Technology)
出处
《临床心血管病杂志》
CAS
北大核心
2020年第6期577-580,共4页
Journal of Clinical Cardiology
关键词
肺动脉高压
心律失常
机械-电反馈
危险因素
pulmonary arterial hypertension
arrhythmias
mechano-electric feedback
risk factor
