摘要
口腔黏膜下纤维性变(oral submucous fibrosis,OSF)是世界卫生组织(World Health Organization,WHO)国际癌症研究中心(International Agency for Research on Cancer,IARC)认定的口腔黏膜潜在的恶性病变。咀嚼槟榔可引起口腔黏膜下纤维性变,其发病与咀嚼槟榔的频率及时间有着密切的量效依赖关系。本文就口腔黏膜下纤维性变是否是一种口腔癌前病变,咀嚼槟榔导致口腔黏膜潜在的恶性病变,以及国外、中国大陆与台湾地区有关该病的研究作一概述,供口腔科医师参考。
Oral submucous fibrosis(OSF)was defined as an oral potentially malignant mucous disorders by the International Agency for Research on Cancer(IARC)of the World Health Organization(WHO).Oral submucous fibrosis was led by chewing betel quid and showed a dose-dependent and time-dependent manner.Whether oral submucous fibrosis is a real oral precancerous lesion or oral potentially malignant disorders led by chewing betel quid,this paper summarizes the present knowledge throughout the foreign countries,Chinese mainland,and Taiwan.
作者
翦新春
高兴
谭茜
JIAN Xinchun;GAO Xing;TAN Qian(Department of Oral and Maxillofacial Surgery,Center of Stomatology,Xiangya Hospital,Central South University,Institute of Oral Precancerous Lesions,Central South University,Changsha 410008,Hunan Province,China)
出处
《口腔颌面外科杂志》
CAS
2020年第4期195-200,共6页
Journal of Oral and Maxillofacial Surgery
基金
国家自然科学基金项目(81260166、81041052、30572044)。
关键词
口腔黏膜下纤维性变
口腔黏膜潜在恶性病变
口腔癌前病变
oral submucous fibrosis(OSF)
oral potentially malignant mucous disorders
oral precancerous lesions
