调督熄风针法配合药物治疗肝阳上亢非杓型高血压疗效观察

Therapeutic Observation of Tiao Du Xi Feng Needling Method Combined with Medication for Non-dipper Hypertension Due to Hyperactivity of Liver Yang

目的观察调督熄风针法配合药物治疗肝阳上亢非杓型高血压的临床疗效及其对血压昼夜节律与脉压差的影响。方法将69例肝阳上亢非杓型高血压患者采用分层随机法随机分为治疗组35例和对照组34例。对照组采用口服马来酸左旋氨氯地平片治疗,治疗组在对照组基础上采用调督熄风针法针刺治疗。观察两组治疗前后各项动态血压值[白天平均收缩压(dMSBP)、白天平均舒张压(dMDBP)、夜间平均收缩压(nMSBP)、夜间平均舒张压(nMDBP)、24 h平均收缩压(24 h MSBP)、24 h平均舒张压(24 h MDBP)]、血压昼夜节律、各项脉压[日间脉压(dMPP)、夜间脉压(nMPP)及24 h平均脉压(24 h MPP)]差值的变化情况,并比较两组临床疗效及杓型高血压转变率。结果两组治疗后各项动态血压值、血压昼夜节律及各项脉压差值与同组治疗前比较差异均具有统计学意义(P<0.05)。治疗组治疗后nMSBP、nMDBP及血压昼夜节律与对照组比较差异均具有统计学意义(P<0.05)。治疗组治疗后总有效率与杓型高血压转变率分别为83.3%和56.7%,对照组分别为66.7%和26.7%,两组比较差异均具有统计学意义(P<0.05)。结论调督熄风针法配合药物是一种治疗肝阳上亢非杓型高血压的有效方法,能调整患者血压昼夜节律。

Objective To observe the clinical efficacy of Tiao Du Xi Feng(regulating the Governor Vessel and extinguishing wind)needling method plus medication in treating non-dipper hypertension due to hyperactivity of liver yang and its effect on the diurnal rhythms of blood pressure and pulse pressure difference.Method Sixty-nine patients with non-dipper hypertension due to hyperactivity of liver yang were divided into a treatment group of 35 cases and a control group of 34 cases using stratified randomization method.The control group was intervened by oral Levoamlodipine maleate tablets and the treatment was given Tiao Du Xi Feng needling in addition to that for the control group.Before and after treatment,the changes in the ambulatory blood pressure parameters[daytime mean systolic blood pressure(dMSBP),daytime mean diastolic blood pressure(dMDBP),night-time mean systolic blood pressure(nMSBP),night-time mean diastolic blood pressure(nMDBP),24-hour mean systolic blood pressure(24 h MSBP),24-hour mean diastolic blood pressure(24 h MDBP)],the diurnal rhythms of blood pressure and the pulse pressure parameters[daytime mean pulse pressure(dMPP),night-time mean pulse pressure(nMPP)and 24-hour mean pulse pressure(24 h MPP)]in the two groups were observed.The clinical efficacy and the conversion rate of non-dipper hypertension were compared between the two groups.Result The ambulatory blood pressure parameters,the diurnal rhythms of blood pressure and the pulse pressure differences changed significantly after treatment in both groups(P<0.05).After treatment,the nMSBP,nMDBP and the diurnal rhythms of blood pressure in the treatment group were significantly different from those in the control group(P<0.05).After treatment,the total effective rate was 83.3%and the conversion rate of non-dipper hypertension was 56.7%in the treatment group,versus 66.7%and 26.7%in the control group,and the between-group differences were statistically significant(P<0.05).Conclusion Tiao Du Xi Feng needling method plus medication is an effective method for non-dipper hypertension due to hyperactivity of liver yang,and it can regulate the diurnal rhythms of blood pressure.