医用臭氧水穴位注射治疗椎动脉型颈椎病临床观察

Clinical Observations on Acupuncture Point Injection of Medical Ozone Water for Cervical Spondylotic Arteriopathy

目的观察医用臭氧水穴位注射治疗椎动脉型颈椎病(cervical spondylotic arteriopathy,CSA)的临床疗效及对脑血流速度的影响。方法80例患者随机分为试验组和对照组,每组40例。试验组采用医用臭氧水穴位注射治疗,对照组采用氟桂利嗪胶囊口服治疗。治疗前后采用症状体征评分、疗效指数(efficacy index,EI)及经颅多普勒探测双侧椎动脉(VA)、基底动脉(BA)、双侧大脑后动脉(PCA)的平均血流速度(Vm),进行评定。结果试验组愈显率和总有效率分别为87.5%、97.5%,均优于对照组的42.5%、70.0%(P<0.05)。两组治疗前症状体征评分比较差异无统计学意义(P>0.05);两组治疗后症状体征评分均比治疗前降低(P<0.05),且试验组低于对照组(P<0.05)。两组治疗前双侧VA、BA、双侧PCA的Vm比较差异无统计学意义(P>0.05);两组治疗后双侧VA、BA、双侧PCA的Vm均比治疗前显著提升(P<0.05),且试验组高于对照组(P<0.05)。结论采用医用臭氧水穴位注射治疗CSA疗效较好,能更有效地改善患者双侧VA、BA、双侧PCA的血流速度。

Objective To investigate the clinical efficacy of acupuncture point injection of medical ozone water for cervical spondylotic arteriopathy(CSA)and its effect on cerebral blood flow velocity.Method Eighty patients were randomized to experiment and control groups,40 cases in each group.The experiment group received acupuncture point injection of medical ozone water and the control group,oral administration of flunarizine capsules.Before and after treatment,an evaluation was made using the symptom and sign score,efficacy index(EI),and mean velocity(Vm)in bilateral vertebral artery(VA),basilar artery(BA)and bilateral posterior cerebral artery(PCA)detected by transcranial Doppler.Result The cure and marked efficacy rate and the total efficacy rate were 87.5%and 97.5%,respectively,in the experiment group,which were significantly higher than 42.5%and 70.0%in the control group(P<0.05).There was no significantly significant pre-treatment difference in the symptom and sign score between the two groups(P>0.05).After treatment,the symptom and sign score decreased in the two groups compared with before(P<0.05)and was lower in the experiment group than in the control group(P<0.05).There were no significantly significant pre-treatment differences in bilateral VA,BA and bilateral PCA Vm between the two groups(P>0.05).After treatment,bilateral VA,BA and bilateral PCA Vm increased significantly in the two groups compared with before(P<0.05)and were higher in the experiment group than in the control group(P<0.05).Conclusion Acupuncture point injection of medical ozone water has a better therapeutic effect on CSA.It can more effectively improve bilateral VA,BA and bilateral PCA blood flow velocity.