婴幼儿皮罗序列征睡眠呼吸评估对治疗的意义

The significance of evaluation of sleep respiration in infants with Pierre Robin sequence

目的:通过PSG对皮罗序列征婴幼儿进行睡眠紊乱的评估,探讨其作为病情客观指标的可行性,了解此类患儿的睡眠呼吸特征。方法:采取PSG对17例皮罗序列征患儿进行>7 h的整夜睡眠监测,记录其睡眠呼吸、血氧等指标,并对监测的结果进行统计和分析。结果:14例(82.35%)皮罗序列征患儿存在不同程度的呼吸暂停、低通气及低氧血症,AHI为12.39±9.86,LSaO2为(84.12±8.12)%。不同性别的皮罗序列征婴幼儿AHI及LSaO2比较差异均无统计学意义,年龄与AHI呈负相关。结论:皮罗序列征多有不同程度的呼吸暂停和低氧血症,需要及早干预,年龄越小病情相对越重,PSG监测可为皮罗序列征的评估提供客观依据,对治疗有重要的指导意义。

Objective:This study aimed to evaluate the sleep disorders of infants with Pierre Robin sequence by PSG,and to understand the sleep breathing characteristics of them.Method:Seventeen patients with Pierre Robin sequence underwent polysomnography lasting over 7 hours.Sleep apnea and oxygen index was recorded and analyzed.Result:14(82.35%)patients with Pierre Robin sequence presented with apnea,hypopnea and hypoxemia with varying degree.The apnea-hypopnea index(12.39±9.86)and lowest arterial oxygen saturation(84.12±8.12)%were not significantly different between sexes.However,age showed a negative impact with apnea-hypopnea index,which was worse in younger infants.Conclusion:Most patients with the Pierre Robin sequence have sleep apnea and hypoxemia,and appropriate management should be implemented in an early age.Polysomnography can provide objective analysis of the treatment.