摘要
目的:研究比较黄河三角洲产地管花肉苁蓉不同极性提取物抗炎镇痛的活性,为其临床试验和进一步应用提供参考依据。方法:采用耳肿胀法和棉球肉芽组织增生法致炎,研究管花肉苁蓉不同极性提取物灌胃给药对急性炎症的作用。采用热板法和醋酸扭体法致痛,研究管花肉苁蓉不同极性提取物灌胃给药的镇痛作用。结果:管花肉苁蓉不同极性提取物对小鼠的耳肿胀、棉球肉芽肿、热板痛阈值时间以及扭体次数有抑制作用,但同模型对照组比较差异不显著。结论:管花肉苁蓉有一定的抗炎镇痛作用。
Purpose:To compare the anti-inflammatory and analgesic activities of different polar extracts of C.tubulosa(Schrenk)Wight from Yellow River delta,and to provide reference for its clinical trial and further application.Methods:Ear swelling and granulation tissue hyperplasia of cotton bulb were used to induce inflammation.Hot plate method and acetic acid writhing method were used to induce pain.Results:Different polar extracts of C.tubulosa(Schrenk)Wight had inhibitory effects on ear swelling,cottonball granuloma,hot plate pain threshold time and twisting times of mice,but the differences were not significant compared with the model control group.Conclusion:C.tubulosa(Schrenk)Wight has certain anti-inflammatory and analgesic effects.
作者
祝梦晓
刘梦亭
白金莲
杨芳丽
房景茹
甘阳
赵文瑄
李亚峻
孙春龙
王宏国
黄莉
杜文
付娟
Zhu Mengxiao;Liu Mengting;Bai Jinlian;Yang Fangli;Fang Jingru;Gan Yang;Zhao Wenxuan;Li Yajun;Sun Chunlong;Wang Hongguo;Huang Li;Du Wen;Fu Juan(College of Biological and Environmental Engineering,Binzhou University,Binzhou 256603,China;Shandong Provincial Engineering and Technology Research Center for Wild Plant Resources Development and Application of Yellow River Delta,Binzhou 256603,China;Shandong Engineering and Technology Research Center for Fragile Ecological Belt of Yellow River Delta,Binzhou 256603,China)
出处
《山东化工》
CAS
2020年第14期19-21,共3页
Shandong Chemical Industry
基金
山东省大学生创新训练计划项目[NO.201910449080]
2019年滨州市社会科学规划重点研究课题[NO.19-SKGH-42]
滨州学院博士基金[NO.2016Y17,2016Y02,2016Y18]
山东省科技发展计划基金[NO.2014GSF119032]。
