叶酸缺乏与常见精神疾病关系研究进展

Research Progress on the Relationship between Folate Deficiency and Commonmentaldisorders

叶酸是一种水溶性维生素,叶酸缺乏不仅可导致胚胎期神经管发育异常,还可能影响大脑功能。笔者就叶酸缺乏与抑郁症、焦虑症、强迫性障碍及精神分裂症等精神疾病的相关性,以及叶酸补充对精神疾病辅助治疗的影响等方面进行综述。

Folate is a water-soluble vitamin.Deficiency of folate may not only lead to abnormal neural tube development in the embryo,but also affect brain function.This paper reviews the association of folate deficiency with depression,anxiety,obsessional disorder,schizophrenia and other psychiatric disorders,as well as the effect of folate supplementation on adjuvant therapy for psychiatric disorders.