基于Mo2C的新型电化学传感器用于色氨酸的检测

A new electrochemical sensor based on Mo2C for the detection of tryptophan

开发了一种基于Mo2C的高灵敏度高催化性新型电化学传感器并用于色氨酸(Trp)的检测。水热一锅法制备Mo2C,通过扫描电镜(SEM)、傅里叶变换红外光谱(FT-IR)和X射线衍射(XRD)对Mo2C纳米复合材料进行表征。在PBS缓冲液中,采用循环伏安法和差分脉冲伏安法研究了Trp在修饰电极上的电化学行为,并对影响实验结果的滴涂量、pH和扫描速度等进行了优化。最佳条件下,色氨酸浓度在10.0~100μmol/L和400~800μmol/L的范围内与Mo2C/GCE电流响应呈良好的线性关系,检测限为3.3μmol/L。

A novel electrochemical sensor based on Mo2C with high sensitivity and catalytic activity was developed for the determination of tryptophan(Trp).Mo2C was prepared by the hydrothermal one-pot method and characterized by scanning electron microscopy(SEM),Fourier transform infrared spectroscopy(FT-IR)and X-ray diffraction(XRD).Cyclic voltammetry and differential pulse voltammetry were used to study the electrochemical behavior of tryptophan at the modified electrode in phosphate buffered saline(PBS)and the factors influencing the experimental results,such as the amount of droplet,pH and scan rate,were optimized.Under the optimal conditions,the current response of Mo2C/GCE was linear with the concentration of tryptophan in the range of 10.0 to 100μmol/L and 400 to 800μmol/L,and the limit of detection was 3.3μmol/L.