积极输血与限制输血用于急性上消化道出血的效果比较

Comparative study of clinical efficacy of active blood transfusion and restricted blood transfusion for acute upper gastrointestinal bleeding

目的探讨在急性上消化道出血的治疗中运用积极输血、限制输血疗法的临床效果。方法选择2018年5月至2019年5月于江门市中心医院实施急性上消化道出血治疗处理的患者98例,应用随机数字表法将患者分为参照组与观察组,每组49例。参照组采用积极输血治疗方案,观察组采用限制输血治疗方案。记录并比较两组中显效、有效、无效等临床治疗结局对应的例数以及临床诊治有效性,观察比较治疗后24、48、72 h等时间节点时两组的成功止血率,比较两组再出血事件的发生率。结果两组临床诊治有效率比较,差异未见统计学意义(P>0.05);治疗后24 h,观察组成功止血率为30.61%(15/49),参照组为12.24%(6/49),差异有统计学意义(P<0.05);治疗后48 h及72 h,两组成功止血率比较,差异未见统计学意义(P>0.05);与参照组比较,观察组再出血事件的发生率明显降低(P<0.05)。结论在急性上消化道出血患者的治疗中应用限制输血疗法相较于积极输血疗法,对成功止血率的提升具有积极意义,且有助于降低再出血事件的发生率。

Objective To investigate the clinical application value of active blood transfusion and limited transfusion therapy in the clinical diagnosis and treatment of patients with acute upper gastrointestinal bleeding.Methods Ninety-eight patients with acute upper gastrointestinal bleeding treated in Jiangmen Central Hospital from May 2018 to May 2019 were selected.The patients were divided into reference group and observation group by digital random table.The two groups were treated with active blood transfusion and limited blood transfusion respectively.The number of cases corresponding to the effective,effective and ineffective clinical treatment outcomes and the effectiveness of clinical diagnosis and treatment in the two groups were compared.The successful hemostasis rates of the two groups at the time of 24,48 and 72 hours after treatment were compared,and the incidences of rebleeding events in the two groups were compared.Results There was no significant difference in the effective rate between the two groups(P>0.05).At 24 hours after treatment,the successful hemostasis rate of the observation group was 30.61%(15/49),that of the reference group was 12.24%(6/49),there was no significant difference(P<0.05).At 48 hours and 72 hours after treatment,there was no significant difference in the successful hemostasis rate between the two groups(P>0.05).Compared with the reference group,the incidence of rebleeding events in the observation group was significantly reduced(P<0.05).Conclusions In the treatment of patients with acute upper gastrointestinal hemorrhage,limited blood transfusion therapy,compared with active blood transfusion therapy,has positive significance for the improvement of the successful hemostasis rate,and helps to reduce the incidence of rebleeding events.