艾滋病患者骨坏死320例临床分析

Clinical analysis of 320 cases of osteonecrosis in acquired immunodeficiency syndrome patients

目的:探讨艾滋病患者骨坏死的临床特征及治疗效果。方法:回顾性分析2016年1月至2020年1月郑州市第六人民医院收治的320例艾滋病骨坏死患者的临床资料,依据病情给予关节置换、髓心钻孔减压、病灶切除后植骨等相应治疗,统计其骨坏死部位、病程、治疗效果。结果:320例患者骨坏死好发于脊柱椎体、双下肢负重关节周围、长管状骨的干骺端等部位,艾滋病病程5~20年,给予相应治疗后患者疼痛评分由8~10分减少至0~1分。结论:艾滋病并发骨坏死患者艾滋病病史较长,骨坏死范围较广,全身多部位广泛性骨坏死者给予综合对症治疗可缓解疼痛症状。

Objective To investigate the clinical features and treatment effects of osteonecrosis in acquired immunodeficiency syndrome(AIDS)patients.Methods The clinical date of 320 AIDS patients with osteonecrosis admitted to the Sixth People’s Hospital of Zhengzhou from January 2016 to January 2020 were retrospectively analyzed.According to the conditions,the patients were given joint replacement,core hole decompression,and bone grafting after lesion resection etc.corresponding treatment,the osteonecrosis site,course of disease,and treatment effect were counted.Results The 320 cases of osteonecrosis occurred in the vertebral body of the spine,around the weight-bearing joints of both lower limbs,the metaphysis of long tubular bones,etc.,and the patient’s course of AIDS was 5 to 20 years.After giving the corresponding treatment,the patient’s pain score decreased from 8-10 points to 0-1point.Conclusions Patients with AIDS and osteonecrosis have a long history of AIDS and a wide range of osteonecrosis.Comprehensive symptomatic treatment can relieve the pain symptoms of the patients with extensive osteonecrosis in multiple parts of the body.