垂体后叶素及缩宫素宫颈注射联合吸宫术+宫腔镜检查术在Ⅰ~Ⅱ型瘢痕妊娠中的应用

Application of cervical injection of Pituitrin and Oxytocin combined with uterine aspiration+hysteroscopy in typeⅠ-Ⅱscar pregnancy

目的探讨垂体后叶素及缩宫素宫颈注射联合吸宫术+宫腔镜检查术在Ⅰ~Ⅱ型瘢痕妊娠中的应用效果。方法选取2018年8月~2019年12月我院收治的98例Ⅰ~Ⅱ型瘢痕妊娠患者作为研究对象,依据随机数字表法将患者分为观察组与对照组,每组各49例。对照组患者给予硬膜外麻醉下经阴道瘢痕妊娠病灶清除术,研究组患者给予垂体后叶素及缩宫素宫颈注射联合吸宫术+宫腔镜检查术。比较两组患者的术中出血量、手术时间、血人绒毛膜促性腺激素(HCG)转阴时间、住院时间、住院费用和并发症发生情况。结果观察组患者的术中出血量少于对照组,手术时间、血HCG转阴时间短于对照组,差异有统计学意义(P<0.05)。观察组患者的住院时间短于对照组,住院费用少于对照组,差异有统计学意义(P<0.05)。观察组患者的并发症总发生率为4.08%,低于对照组的16.33%,差异有统计学意义(P<0.05)。结论垂体后叶素及缩宫素宫颈注射联合吸宫术+宫腔镜检查术治疗Ⅰ~Ⅱ型瘢痕妊娠的效果显著,能够缩短患者的治疗时间,减少出血,且无手术切口,并发症少,值得临床推广应用。

Objective To explore the application effect of cervical injection of Pituitrin and Oxytocin combined with uterine aspiration+hysteroscopy in typeⅠ-Ⅱscar pregnancy.Methods A total of 98 patients with typeⅠ-Ⅱscar pregnancy who were admitted to our hospital from August 2018 to December 2019 were selected as research subjects.According to the random number table method,the patients were divided into observation group and control group,with 49 cases in each group.The control group was given removal of transvaginal scar pregnancy lesions under epidural anesthesia,and the study group was given cervical injection of Pituitrin and Oxytocin combined with uterine aspiration+hysteroscopy.The intraoperative blood loss,surgery time,negative conversion time of blood human chorionic gonadotropin(HCG),length of hospital stay,hospitalization cost and complications were compared between the two groups.Results The intraoperative blood loss in the observation group was less than that in the control group,the surgery time and the negative conversion time of blood HCG were shorter than those in the control group,the differences were statistically significant(P<0.05).The length of hospital stay in the observation group was shorter than that in the control group,and the hospitalization cost was less than that in the control group,the differences were statistically significant(P<0.05).The total incidence rate of complications in the observation group was 4.08%,which was lower than 16.33%in the control group,and the difference was statistically significant(P<0.05).Conclusion Cervical injection of Pituitrin and Oxytocin combined with uterine aspiration+hysteroscopy in the treatment of typeⅠ-Ⅱscar pregnancy has a significant effect,which can shorten the treatment time and reduce bleeding,and there is no surgical incision and fewer complications,which is worthy of clinical promotion and application.