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动脉粥样硬化易损斑块血清标志物研究进展 被引量:5

Research progress on serum markers of vulnerable atherosclerotic plaque
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摘要 动脉粥样硬化斑块的破裂或腐蚀继发血栓形成是急性心脑血管事件发生的病理基础。根据不稳定斑块的形成机制,血清标志物可分为两大类。酶解作用标志物通过降解细胞外基质引起纤维帽变薄,促进不稳定斑块形成;促炎性细胞因子标志物则通过扩大炎性级联反应,参与动脉粥样硬化的发生发展。该文主要介绍两类标志物与斑块稳定性的关系。
作者 秦雅红 张振刚 何维 刘海威 李晨 焦云根 QIN Yahong;ZHANG Zhengang;HE Wei
出处 《国际心血管病杂志》 2020年第4期196-200,共5页 International Journal of Cardiovascular Disease
基金 国家自然科学基金(81770262) 扬州市“十三五”科教强卫专项经费资助(重点人才ZDRC201817)。
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