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12-脂氧合酶与结直肠癌的研究进展 被引量:1

Research Progress in the Relationship Between 12-lipoxygenase and Colorectal Cancer
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摘要 花生四烯酸是人体内重要的不饱和脂肪酸,12-脂氧合酶可催化花生四烯酸产生多种生物活性物质。其代谢通路在肿瘤的发生发展中起着重要作用,尤其是12-脂氧合酶与结直肠癌之间的关系已成为近年来研究的热点,现主要对二者关系的研究进展予以综述。 Arachidonic acid is an important unsaturated fatty acid in human body.12-lipoxygenase can catalyze arachidonicacid to produce a variety of bioactive substances.Its metabolic pathway plays an important role in the development of tumor,in par-ticular,the relationship between 12-lipoxygenase and colorectal cancer has become a research hotpot in recent years,the articlereviews the research progress of the relationship between 12-lipoxygenase and colorectal cancer.
作者 许琳 XU Lin(Department of Pathology,Tianjin Public Security Hospital,Tianjin,300042,China)
出处 《黑龙江医学》 2020年第8期1160-1162,共3页 Heilongjiang Medical Journal
基金 天津市公安局科研基金(2016KYSGAY033)。
关键词 12-脂氧合酶 结直肠癌 抑制剂干预 12-lipoxygenase Colorectal cancer Inhibitor intervention
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