益气养血汤治疗功能性肛门直肠痛临床疗效观察

Clinical observation of Yiqi Yangxue Decoction in the treatment of functional anorectal pain

[目的]评价益气养血汤内服治疗功能性肛门直肠痛(FAP)的临床疗效。[方法]选取40例FAP患者,采用随机数字表法分为观察组和对照组各20例。观察组采用益气养血汤加温水坐浴治疗;对照组采用温水坐浴。2周为1个疗程,共2个疗程。分析比较两组患者治疗前后疼痛视觉模拟评分(VAS)、焦虑及抑郁自评分(SDS)、SF-36生活质量评分、治疗效果评估。采用SPSS 24.0软件进行统计分析。[结果]观察组治疗总有效率85.00%显著高于对照组的55.00%(P<0.05);观察组治疗后VAS评分显著低于对照组及治疗前(P<0.05);观察组及对照组治疗后焦虑及抑郁自评分(SAS、SDS)均显著低于治疗前,但观察组评分更低(P<0.05);观察组及对照组治疗后SF-36生活质量评分均显著高于治疗前,但观察组评分更高(P<0.05)。[结论]益气养血汤口服治疗功能性肛门直肠痛能够取得良好的临床疗效,改善患者预后。

[Objective]To evaluate the clinical effect of Yiqi Yangxue Decoction on functional anorectal pain.[Methods]Forty FAP patients were selected and randomly divided into observation group and control group with 20 cases each.The observation group was treated with Yiqi Yangxue Decoction combined with warm water sitz bath.The control group was only treated with warm water sitz bath.Two weeks is a course of treatment,a total treatment of two courses.The self-score of Visual analogue scale(VAS),Self-rating Anxiety Scale(SAS),Self-rating Depression Scale(SDS),SF-36 quality of life score and clinical effect before and after treatment were analyzed and compared between the two groups.SPSS 24.0 software was used for statistical analysis.[Results]The total effective rate of the observation group was 85.00%,which was significantly higher than that of the control group(55.00%,P<0.05).After treatment,the VAS scores in the observation group were significantly lower than those in the control group and before treatment(P<0.05);the SAS and SDS scores in the observation group and the control group were significantly lower than those before treatment,but the scores in the observation group were lower than those in the control group(P<0.05);the SF-36 quality of life scores in the observation group and the control group were significantly higher than those before treatment,but the scores in the observation group were higher than those in the control group(P<0.05).[Conclusion]Yiqi Yangxue Decoction in the treatment of functional anorectal pain can obtain good clinical effect,helps to improve the prognosis.