原发性IgA肾病与尿红细胞形态的相关性

Correlations of urine erythrocyte morphology with primary IgA nephropathy

目的观察原发性IgA肾病病理分型与尿中红细胞形态,并与其他原发性肾小球肾炎患者尿红细胞形态比较,分析原发性IgA肾病是否有其独特的特征.方法统计2012年1月—2018年12月在中国人民解放军总医院第六医学中心进行肾穿后刺活检诊断为IgA肾病的患者尿液检查中是否出现红细胞及不同红细胞出现的比例,与其他原发性肾炎中红细胞形态做比较,并统计不同Lee氏分级中红细胞形态.结果原发性IgA肾病患者尿红细胞形态主要包括圆形、面包圈样、G1型红细胞和棘形,其中较有特征的是G1型红细胞和有时可见小圆形红细胞聚集成团;根据Lee氏分级的不同,不同红细胞所占比例也有相应的改变.结论尿红细胞形态可以部分反应原发性IgA肾病及病理类型.

Objective The study is to find out whether urine erythrocyte morphology has its unique characteristics in primary IgA nephropathy and its pathological type by comparing with other patients of primary glomerulonephritis.Methods Red blood cells appeared in urine examination and the proportion of different red blood cells in different Lee’s grades,to evaluate the patients diagnosed with primary IgA nephropathy and other primary glomerulonephritis from January 2012 to December 2018 in the Sixth Medical Center of Chinese PLA General Hospital.Results Urine erythrocyte morphology in patients with primary IgA nephropathy mainly includes:microspherocyte,doughnut,G1 red blood cell and spinos.Those with G1 and aggregative microspherocyte red blood cells are special.And the proportion of different erythrocytes also changed accordingly to the Lee’s grade.Conclusion Urine erythrocyte morphology can partly reflect primary IgA nephropathy and its pathological type.