高龄患者腹腔镜下行前列腺癌根治性切除术围手术期并发症及预后研究

Perioperative complications and prognosis of laparoscopic radical prostatectomy in elderly patients

目的探讨高龄患者行腹腔镜前列腺根治性切除术(LRP)围手术期并发症发生及预后。方法选取2012年1月至2017年12月在本院收治的116例高龄前列腺癌(PCa)患者(≥75岁),均行LRP术,分析围手术期发生并发症、手术时间、术中出血量和术后住院时间等情况。围手术期并发症定义为术后30 d内发生的并发症。结果平均手术时间175.8 min,平均出血量154.7 mL。术后平均住院时间15.9 d。围手术期并发症发生率33.6%(39例),包括尿漏、尿路感染、肺炎、下肢静脉血栓、肺栓塞等。结论LRP术仍有较高的并发症发生率,术前应积极治疗基础疾病,术中严格操作,术后采取相应预防措施以防止出现严重并发症,并根据患者情况选择合适的治疗方案。

Objective To evaluate operation process and perioperative complications of elderly patients who underwent laparoscopic radical prostatectomy(LRP).Methods The clinical data of 116 cases of LRP were reviewed retrospectively.Perioperative complications were analyzed,and so were the operative time,blood loss and postoperative hospital stay.Perioperative complications were defined as any adverse event with in 30 days of surgery.Results The mean operation time was 175.8 minutes,the mean blood loss was 154.7 mL,the average postoperative hospital stay was 15.9 d.A total of 39 patients(33.6%)developed at least one perioperative complication.which included urinary leakage,urinary tract infections,deep venous thrombosis of the lower limbs,pneumonia,etc.Conclusions Morbidity of perioperative complications following LRP is still high.The most frequent complications are ileus and urinary tract infections.Preventive measures should be taken to prevent serious complications.And we should choose an appropriate treatment procedure according to the patient's condition.