丁苯酞软胶囊治疗缺血性脑血管病患者的效果

Effect of Butylphthalide Soft Capsule in Treating Ischemic Cerebrovascular Disease

目的观察丁苯酞软胶囊治疗缺血性脑血管病的临床效果。方法选取2018年5月至2019年5月遵化市人民医院收治的缺血性脑血管病患者98例,按照随机数字表法分成治疗组与对照组,各49例。对照组使用阿司匹林治疗,治疗组使用丁苯酞药物治疗,比较其疗效与各项指标。结果治疗组有效率为97.96%,对照组为83.67%,治疗组高于对照组,差异有统计学意义(P<0.05)。使用药物1个月后,治疗组同型半胱氨酸为(13.1±0.9)μmol/L、血管内皮细胞生长因子为(133.4±47.2)ng/mL、一氧化氮为(33.8±5.2)U/mL、脑卒中量表(NIHSS)评分为(4.5±2.1)分;对照组分别为(15.3±1.2)μmol/L、(296.4±86.1)ng/mL、(66.8±13.4)U/mL、(11.8±3.6)分,治疗组均优于对照组,差异有统计学意义(P<0.05)。结论在脑血管病的临床治疗中,丁苯酞软胶囊具有良好的治疗效果,能够促进患者脑部血液循环,促进神经功能恢复。

Objective To observe the clinical effect of butylphthalide soft capsule in the treatment of ischemic cerebrovascular disease.Methods A total of 98 patients with ischemic cerebrovascular disease admitted to Zunhua People's Hospital from May 2018 to May 2019 were selected and divided into treatment group and control group according to the random number table method,with 49 patients in each group.The control group was treated with aspirin,while the treatment group was treated with butylphthalide.Results The effective behavior of the treatment group was 97.96%,and that of the control group was 83.67%.The treatment group was better than the control group(P<0.05),showing statistical difference.After one month of treatment,homocysteine was(13.1±0.9)μmol/L,endothelial cell growth factor was(133.4±47.2)ng/mL,nitric oxide was(33.8±5.2)U/mL,and NIHSS score was(4.5±2.1).The control group was(15.3±1.2)mol/L,(296.4±86.1)ng/mL,(66.8±13.4)U/mL,and(11.8±3.6)score,respectively.The treatment group was better than the control group(P<0.05),showing statistical difference.Conclusion In the clinical treatment of cerebrovascular disease,butylphthalide capsule has a good therapeutic effect,can promote the brain blood circulation of patients,promote the recovery of nerve function.