血栓抽吸术对超急性期的STEMI患者介入治疗中慢血流/无复流的影响

Influence of thrombus aspiration on slow flow/no reflow in hy peracute phase STEMI patients during PCI

目的:研究血栓抽吸术对超急性期的急性ST段抬高型心肌梗死(STEMI)患者经皮冠脉介入治疗(PCI)过程中冠脉慢血流/无复流发生的影响.方法:选择我院超急性期STEMI且行PCI术的患者100例,根据PCI过程是否使用冠脉内血栓抽吸分为血栓抽吸组(48例)和常规PCI组(52例),观察并比较两组PCI术中慢血流/无血流及并发症发生情况、术后一年临床主要不良心血管事件(MACE)发生率.结果:与常规PCI组比较,血栓抽吸组PCI术中慢血流/无复流发生率(15.38%比2.08%)及术后随访一年临床MACE总发生率(42.31%比16.67%)均显著降低(P分别=0.020,0.005).结论:血栓抽吸术可显著减少超急性期的STEMI患者介入治疗过程中冠脉慢血流/无复流的发生,同时能显著降低患者术后一年临床主要不良心脏事件的发生率.

Objective:To study influence of thrombus aspiration(TA) on coronary slow flow/no reflow during percutaneous coronary intervention(PCI) in hyperacute phase patients with acute ST elevation myocardial infarction(STEMI). Methods:A total of 100 hyperacute phase STEMI patients undergoing PCI hospitalized in our hospital were selected. According to use of intracoronary TA during PCI or not, they were divided into TA group(n=48) and routine PCI group(n=52). Incidence of slow flow/no reflow and complications during PCI, major adverse cardiovascular events(MACE) within one-year follow-up after PCI were observed and compared between two groups. Results:Compared with routine PCI group, there were significant reductions in incidence rate of slow flow/no reflow during PCI(15.38% vs. 2.08%) and total incidence rate of MACE within one-year follow-up after PCI(42.31% vs. 16.67%) in TA group, P=0.020, 0.005 respectively. Conclusion:Thrombus aspiration can significantly reduce incidence of coronary slow flow/no reflow during PCI in hyperacute phase STEMI patients. And it can significantly reduce incidence rate of MACE within one year after PCI.