山东某高校教职工高尿酸血症患病情况及相关因素分析

Hyperuricemia situation and its related factors of faculty in a university in Shandong Province

目的了解高校教职工群体高尿酸血症(HUA)患病情况及相关因素分析,为疾病预防提供依据。方法对2018年5-7月山东某高校2 553名教职工在当地三甲医院的健康体检结果进行回顾性分析,用SPSS 22.0统计软件分析HUA患病相关因素。结果 2018年本校教职工HUA患病率15.20%(388/2553),男性HUA患病率18.63%(272/1460),女性HUA患病率10.61%(116/1093),男性多于女性,(P<0.05);男性30~50岁HUA患病率较高为20.83%(115/552);女性51~60岁HUA患病率较高为9.84%(30/305)。体质指数(BMI)、血压、血糖、三酰甘油、低密度脂蛋白、总胆固醇、尿素氮、肌酐异常组HUA患病率较高,分别为20.90%、20.30%、12.60%、26.30%、20.80%、20.80%、20.4%、30.2%;BMI、血压、血糖、三酰甘油、低密度脂蛋白、总胆固醇、尿素氮、肌酐正常者HUA患病率低,分别为8.50%、12.50%、15.50%、11.30%、13.80%、13.80%、15.10%、14.70%。体检指标异常组HUA患病率高于正常组,差异有统计学意义(P<0.05)。结论该校教职工30~60岁高尿酸血症的患病率高,应积极调整生活方式和饮食习惯,定期体检,加强疾病预防及保健意识,提前干预高尿酸血症疾病发生。

Objective To understand the hyperuricemia(HUA) and its related factors in faculty of universities, so as provide the evidence for early prevention of HUA.MethodsThe data of physical examinations of 2 553 teaching and administrative staff were collected and retrospectively analyzed by SPSS 22.0 from May 2018 to July 2018.Results The prevalence of HUA in the faculty was 15.20%(388/2553). The positive rate of HUA was 18.63%(272/1460) in the males,and10.61%(116/1093)inthefemales,andtheformerwashigherthanthelatter(P<0.05). The positive rate of the male faculty aged 30-50 years was 20.83%(115/552), while the positive rate of the female faculty aged 51-60 years was 9.84%. The positive rates of people who had abnormal BMI, blood pressure, blood glucose, triglyceride, low density lipoprotein, total cholesterol, urea nitrogen, and creatinine were 20.90%, 20.30%, 12.60%, 26.30%, 20.80%, 20.80%, 20.4% and 30.2%respectively, which were higher than the mean levels. The positive rates of people who had normal BMI, blood pressure,blood glucose, triglyceride, low density lipoprotein, total cholesterol, urea nitrogen, and creatinine were 8.50%, 12.50%,15.50%, 11.30%, 13.80%, 13.80%, 15.10% and 14.70% respectively, which were lower than the mean levels. The prevalence of HUA in the group with abnormal physical examination indexes was higher than that in the group with normal physical examination indexes(P<0.05).ConclusionThe positive rate of HUA was higher among the staff aged 30-60 years. Therefore, they should adjust their healthy lifestyles and healthy eating habits, and they should also have regular physical examinations and enhance the awareness of disease prevention and control.