血清降钙素原在Stanford A型主动脉夹层患者术后肺部感染的预测及预后评估价值

The value of serum PCT in the prediction and prognosis of postoperative pulmonary infection in patients with Stanford type A aortic dissection

目的探讨血清降钙素原(PCT)对Stanford A型主动脉夹层患者术后发肺部感染的预测及预后评估价值。方法选取2018年1月至2019年5月期间华中科技大学同济医学院附属同济医院收治的Stanford A型主动脉夹层并接受手术治疗的82例患者作为研究对象,依据其术后是否发生肺部感染分为52例感染组及30例对照组(未感染患者),采集两组患者的一般临床资料及术前、术后2d、术后3d的静脉血样本,检测其PCT及WBC水平。结果感染组住院时间及预后死亡人数明显高于对照组,差异有统计学意义(P<0.05)。感染组术后3dPCT水平明显高于对照组,差异有统计学意义(P<0.05)。感染组好转患者术后2d、术后3d的PCT水平与死亡患者比较,差异有统计学意义(P<0.05)。结论监测血清PCT水平对Stanford A型主动脉夹层患者术后发生肺部感染的预测及预后判断有一定的参考价值。

Objective To explore the effect of serum procalcitonin(PCT)on the prediction and prognostic value in postoperative pulmonary infection after Stanford type A aortic dissection surgery.Methods 82 patients with Stanford type A aortic dissection admitted in Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology from January 2018 to may 2019 were divided into infection group(n=52)and control group(uninfected patients,n=30)according to their postoperative pulmonary infection.The general clinical data of the two groups and the venous blood samples before,on the second day and on the third day were collected and the PCT and WBC levels were detected.Results The length of hospital stay and number of prognostic deaths in the infected group were significantly higher than those in the control group,the difference was statistically significant(P<0.05).The PCT level in the infection group was significantly higher than that in the control group 3 days after operation,the difference was statistically significant(P<0.05).The PCT levels of the improved patients in the infection group at 2 dand 3 dafter operation were compared with those of the dead patients,the difference was statistically significant(P<0.05).Conclusion Postoperative monitoring of serum PCT level has a certain reference value for the prediction of pulmonary infection and prognosis in patients with Stanford type A aortic dissection.