519例胎儿宫内生长受限发生的危险因素及妊娠结局

Risk factors and pregnancy outcomes of 519 fetuses with intrauterine growth restriction

目的分析519例胎儿宫内生长受限(IUGR)发生的危险因素及妊娠结局。方法纳入在我院分娩的IUGR产妇519例作为研究组,选择同期分娩正常体质量新生儿的产妇400例为对照组。比较两组的临床资料、妊娠结局,分析IUGR发生的危险因素。结果Logistic二元回归结果显示,HDP、羊水过少、胎盘异常、脐带异常、子宫肌瘤和宫内感染均为IUGR发生的独立危险因素(P<0.05)。研究组胎儿窘迫、新生儿窒息和剖宫产的发生率均明显高于对照组(P<0.05)。结论对于合并HDP、羊水过少、胎盘异常、脐带异常、子宫肌瘤和宫内感染的IUGR高危孕妇,当胎儿生长发育缓慢时,应及时了解发病原因,必要时给予医疗干预,以改善妊娠结局,提高新生儿的生存质量。

Objective To analyze the risk factors and pregnancy outcomes of 519 fetuses with intrauterine growth restriction(IUGR).Methods A total of 519 IUGR puerperas who delivered in our hospital were enrolled as study group,400 puerperas who gave birth to normal-weight newborns in the same period were selected as control group.The clinical data and pregnancy outcomes of the two groups were compared,and the risk factors of IUGR were analyzed.Results Logistic binary regression showed that HDP,oligohydramnios,placental abnormalities,umbilical cord abnormalities,uterine fibroids and intrauterine infection were independent risk factors of IUGR(P<0.05).The incidences of fetal distress,neonatal asphyxia and cesarean section in the study group were significantly higher than those in the control group(P<0.05).Conclusion For high-risk pregnant women with IUGR who have HDP,oligohydramnios,placental abnormalities,umbilical cord abnormalities,uterine fibroids and intrauterine infections,when the fetal growth and development is slow,the cause of the disease should be understood in time,and medical intervention should be given if necessary to improve the pregnancy outcome and the quality of life of the newborn.