摘要
目的:探讨影响冠状动脉粥样硬化性心肌病(简称冠心病)血瘀证发生的相关危险因素。方法:选择2016年1月至2018年5月于海南省中医院心血管内科就诊的292例冠心病患者为研究对象,根据是否为血瘀证分为冠心病血瘀证组175例与非血瘀证组117例。选择可能影响冠心病血瘀证的临床指标进行单因素分析及多因素非条件logistic回归方法。结果:单因素分析显示,年龄、体质指数(body mass index,BMI)、高压病史、糖尿病史、吸烟史、食用油消耗、食盐消耗、睡眠状况、体育锻炼、情绪问题及实验室指标总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG),高密度脂蛋白(high density lipoprotein cholesterol,HDL-C)、低密度脂蛋白(low-density lipoprotein cholesterol,LDL-C)脂蛋白相关磷脂酶A2(Lp-PLA2)与冠心病血瘀证密切相关(P<0.05)。多因素Logistic回归模型发现影响冠心病血瘀证的独立危险因素有高血压病史(OR=2.221)、糖尿病史(OR=3.159)、食用油消耗(OR=1.551)、食盐消耗(OR=1.738)、体育锻炼(OR=0.471)、情绪问题(OR=1.388)、Lp-PLA2(OR=2.030),其中体育锻炼为保护性因素。结论:高压病史、糖尿病史、食用油消耗、食盐消耗、体育锻炼、情绪问题、Lp-PLA2是影响冠心病血瘀证的独立危险因素,其中体育锻炼为保护性因素。
Objective:To explore the related risk factors of coronary heart disease of blood stasis pattern.Methods:All 292 CHD patients who visited cardiovascular medicine department of Hainan Provincial TCM Hospital were selected as the research objects between January,2016 and May,2018,and they were allocated to blood stasis group(175 cases)and non blood stasis group(117 cases)according to whether the patients were of blood stasis pattern.Clinical indexes which might affect CHD of blood stasis pattern were chosen to perform single-factor analysis and multivariate logistic regression method.Results:Single-factor analysis showed that age,BMI,hypertension history,diabetes history,smoking history,cooking oil consumption,salt consumption,sleeping status,physical exercise,emotional problems,lab indexes such as TC,TG,HDL-C,LDL-C and Lp-PLA2 were closely related to CHD of blood stasis pattern(P<0.05).Multivariate Logistic regression model suggested that the independent risk factors of influencing CHD of blood stasis pattern were hypertension history(OR=2.221),diabetes history(OR=3.159),cooking oil consumption(OR=1.551),salt consumption(OR=1.738),physical exercise(OR=0.471),emotional problems(OR=1.388)and Lp-PLA2(OR=2.030),among them,physical exercise was the protec-tive factor.Conclusion:Hypertension history,diabetes history,cooking oil consumption,salt consumption,physical exercise,emotional problems and Lp-PLA2 are the independent risk factors of influencing CHD of blood stasis pattern,among them,physical exercise is the protective factor.
作者
黄正新
黄献平
及孟
杨振宇
林冬晶
HUANG Zhengxin;HUANG Xianping;JI Meng;YANG Zhenyu;LIN Dongjing(Cardiovascular Medicine Department,Hainan Provincial Hospital TCM,Haikou 570203,China;TCM Diagnostic Lab,Hunan University of Chinese Medicine)
出处
《西部中医药》
2020年第6期67-70,共4页
Western Journal of Traditional Chinese Medicine
基金
湖南省教育厅科学研究重点项目(15A143)
湖南省中医药科研计划项目(201559)。
关键词
冠心病
血瘀证
危险因素
LOGISTIC回归分析
coronary heart disease
blood stasis patterm
risk factor
Logistic regression analysis