非妊娠妇女阴道真菌感染情况调查

Investigation of vaginal fungal infections in non-pregnant women

目的了解非妊娠期妇女阴道真菌感染情况,并分析与其他阴道病原微生物感染的联系。方法回顾性分析354例接受阴道微生物全面检查的非妊娠妇女临床资料,分析不同年龄、文化程度、阴部卫生习惯、性生活习惯及其他阴道病原微生物感染情况下阴道真菌感染发生率差异。结果354例受试妇女共检出102例(28.81%)存在阴道真菌感染,分离出115株真菌,其主要构成为白念珠菌、光滑念珠菌及热带念珠菌。不同文化程度、内裤更换频次、卫生护垫使用习惯、阴道冲洗频次、口服避孕药应用史及阴道细菌、支原体/衣原体感染条件妇女阴道发生真菌感染率比较均有统计学意义(P<0.05),但不同年龄、内裤材质、性生活频次、安全套使用习惯及阴道滴虫感染条件妇女阴道发生真菌感染率比较均无统计学意义(P>0.05)。结论非妊娠妇女阴道真菌感染与多种因素相关,临床需对相应高危人群展开系统而全面的健康教育,并重视对其他阴道病原微生物阳性患者真菌感染情况的早期筛查。

Objective To understand the vaginal fungal infections in non-pregnant women and to analyze its association with other pathogenic microbial infections.Methods The clinical data of 354 non-pregnant women who underwent comprehensive examination of vaginal microbes were retrospectively analyzed,and the differences in the incidence rates of vaginal fungal infections were analyzed under different ages,educational levels,genital hygiene habits,sexual habits and other vaginal pathogenic microbial infections.Results A total of 102 cases(28.81%)of the 354 women were found to have vaginal fungal infections,and 115 fungi strains were isolated,and mainly were Candida albicans,Candida glabrata and Candida tropicalis.There was a statistically significant difference in the vaginal fungal infection rates among women with different educational levels,frequency of underwear replacement,habit of hygienic pad,frequency of vaginal washing,application history of oral contraceptives and infection of vaginal bacteria and mycoplasma/chlamydia(P<0.05).However,there was no statistically significant difference in vaginal fungal infection rate among women of different ages,underwear materials,frequency of sexual life,condom use habits and vaginal trichomoniasis infection(P>0.05).Conclusion Vaginal fungal infection in non-pregnant women is associated with a variety of factors.It is necessary to carry out systematic and comprehensive health education for the corresponding high-risk groups,and to pay attention to the early screening of fungal infections in patients with other positive vaginal pathogenic microbes.