地塞米松联合强的松治疗儿童分泌性中耳炎对患儿病情复发率的影响

Analysis of the effect of dexamethasone combined with prednisone on recur rence rate of secretory otitis media in children

目的:探讨并分析用地塞米松联合强的松治疗儿童分泌性中耳炎(secretory otitis media,SOM)的临床效果及对患儿病情复发率的影响。方法:将2017年6月至2019年9月山西省儿童医院收治的86例SOM患儿随机分为糖皮质激素组(GC组,n=43)与常规治疗组(RT组,n=43)。对两组患儿均进行常规治疗,在此基础上用地塞米松联合强的松对GC组患儿进行治疗,然后比较两组患儿的临床疗效及治疗后12个月其病情的复发率。结果:GC组患儿治疗的总有效率高于RT组患儿,P<0.05。治疗后12个月内,GC组患儿病情的复发率低于RT组患儿,P<0.05。结论:对SOM患儿进行常规治疗的基础上,用地塞米松联合强的松对其进行治疗能显著提高其疗效,降低其病情的复发率。

Objective:To investigate and analyze the clinical effect of dexamethasone combined with predtisone in the treatment of secretory Otitis media(SOM)in children and its effect on the recurrence rate of secretory otitis media(SOM)in children.Methods:86 SOM children admitted to Shanxi Children’s Hospital from June 2017 to September 2019 were randomly divided into glucocorticoid group(GC group,n=43)and routine treatment group(RT group,n=43).The two groups of children were routinely treated,on this basis,dexamethasone combined with prednisone was used to treat the children in the GC group,and then the clinical efficacy of the two groups of children and the recurrence rate of the disease 12 months after treatment were compared.Results:The total effective rate in GC group was higher than that in RT group(P<0.05).Within 12 months after treatment,the recurrence rate of GC group was lower than RT group(P<0.05).Conclusion:Dexamethasone combined with prednisone can significantly improve the curative effect and reduce the recurrence rate of SOM children on the basis of routin e treatment.