盐酸拉贝洛尔联合硝苯地平治疗重度子痫前期的效果研究

Efficacy of labelol hydrochloride combined with nifedipine in the treatment of severe preeclampsia

目的:探讨联用盐酸拉贝洛尔和硝苯地平对重度子痫前期患者进行治疗的临床效果。方法:选取2018年10月至2019年10月在山东省妇幼保健院进行治疗的150例重度子痫前期患者作为研究对象。将其随机平均分为甲组和乙组。使用硝苯地平对甲组患者进行治疗。联用盐酸拉贝洛尔和硝苯地平对乙组患者进行治疗。然后,比较两组患者的收缩压、舒张压、尿液中蛋白质的含量及妊娠期并发症的发生情况。结果:治疗期间,乙组患者妊娠期并发症的总发生率低于甲组患者,P<0.05。治疗后,乙组患者的收缩压和舒张压均低于甲组患者,P<0.05;乙组患者尿液中蛋白质的含量少于甲组患者,P<0.05。结论:联用盐酸拉贝洛尔和硝苯地平对重度子痫前期患者进行治疗,可控制其血压,降低其妊娠期并发症的发生率。

Objective:To investigate the clinical effect of rabelol hydrochloride combined with nifedipine in the treatment of severe preeclampsia.Methods:150 patients with severe preeclampsia who were treated in Shandong Maternal and Child Health Hospital from October 2018 to October 2019 were selected as study subjects.They were randomly divided into group A and Group B.Nifedipine was used to treat patients in group A.Labelol hydrochloride and nifedipine were used to treat the patients in group B.Systolic blood pressure,diastolic blood pressure,protein content in urine and complications during pregnancy were then compared between the two groups.Results:During treatment,the total incidence of pregnancy complications in group B was lower than that in group A(P<0.05).After treatment,systolic blood pressure and diastolic blood pressure in group B were lower than those in group A(P<0.05).The protein content in the urine of patients in group B was less than that of patients in group A(P<0.05).Conclusion:Rabelol hydrochloride combined with nifedipine can control the blood pressure and reduce the incidence of pregnancy complications in patients with severe preeclampsia.