免煎中药配方颗粒与传统中药饮片治疗慢性胃炎的效果对比

Comparison of the effect of Decoction granules with traditional Chinese m edicine on chronic gastritis

目的:分析并比较用免煎中药配方颗粒与传统的中药饮片治疗慢性胃炎的临床效果。方法:将2017年11月至2018年11月期间朔州市中心医院收治的98例慢性胃炎患者随机分为中药配方颗粒组(CHFG组,n=49)与中药饮片组(TCM组,n=49)。对两组患者均进行常规治疗,在此基础上分别用免煎中药配方颗粒与传统的中药饮片对CHFG组患者与TCM组患者进行治疗,然后比较两组患者的临床疗效及其血清炎性细胞因子的水平。结果:CHFG组患者治疗的总有效率高于TCM组患者,P<0.05。治疗2个月后,CHFG组患者血清超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)的水平均低于TCM组患者,P<0.05。结论:与用传统的中药饮片治疗慢性胃炎相比,用免煎中药配方颗粒治疗该病的效果更好,能更有效地缓解患者的病情,改善其血清炎性细胞因子的水平。

Objective:To analyze and compare the clinical effect of treating chronic gastritis with traditional Chinese medicine decoction pieces and non-decoction Chinese medicine granule.Methods:A total of 98 patients with chronic gastritis admitted to Shuozhou Central Hospital from November 2017 to November 2018 were randomly divided into TCM formula granule group(CHFG group,n=49)and TCM decoction slice group(TCM group,n=49).For the two groups of patients are routine treatment,on this basis,respectively use the decoction of traditional Chinese medicine granule and traditional Chinese medicine decoction pieces to CHFG group and TCM group patients for treatment,and then compare the two groups of patients with clinical efficacy and the level of serum inflammatory cytokines.Results:The total effective rate in CHFG group was higher than that in TCM group(P<0.05).After 2 months of treatment,the serum levels of hS-CRP,IL-6 and TNF-in CHFG group were all lower than those in TCM group(P<0.05).Conclusion:Compared with treating chronic gastritis with traditional Chinese medicine decoction slices,treating chronic gastritis with Non-decocted Chinese medicine granule has better effect,can alleviate patients’condition more effectively,and improve the level of serum inflammatory cytokines.