神经肌肉病患者功能评定的临床应用进展

Advance in Clinical Functional Assessment of Neuromuscular Disease(review)

大部分神经肌肉病属于罕见病,其中相对较为常见的是Duchenne型肌营养不良和脊髓性肌萎缩症。神经肌肉病的一个重要特征是进行性残疾,因此功能评定对评价神经肌肉病患者的疾病严重程度、运动功能以及活动能力非常重要。目前功能评定包括肌力、关节活动度、姿势、活动能力等方面,涉及多种评定工具,但尚未形成统一标准。精确、合理的评定方法对多学科管理团队为患者制定个体化治疗方案具有重要意义。

Most of the neuromuscular diseases are rare diseases,and Duchenne muscular dystrophy and Spinal muscular atrophy are common types of neuromuscular diseases.An important feature of neuromyopathy is progressive disability.Therefore,functional assessment is very important to evaluate the severity,motor function and activities of patients with neuromuscular disease.At present,the functional assessment invoved muscle strength,range of motion,posture and activities,and applied various functional assessment tools.However,there is no unified standard yet.Accurate and reasonable evaluation is essential for multidisciplinary management team to develop individualized treatment plan for patients.