疏通矫正手法对cblC型甲基丙二酸尿症患儿功能的效果

Effect of Dredging Correcting Manipulation on Stunting in Children with cblC Methylmalonic Aciduria

目的探讨疏通矫正手法对cblC型甲基丙二酸尿症(MMA)患儿功能的效果。方法2017年10月至2018年10月,本院收治的cblC型MMA伴发育迟缓3~36月龄的患儿72例,根据家长意愿分为对照组(n=36)和试验组(n=36)。对照组采用常规西药治疗,试验组在此基础上加用疏通矫正手法治疗。采用中文版Griffiths发育量表(GDS-C)进行发育评估,同时测定身长、体质量和头围。结果对照组脱落6例,试验组脱落5例。治疗前,两组GDS-C各领域和总发育商均无显著性差异(P>0.05)。治疗后,两组GDS-C各领域发育商和总发育商均显著升高(t>6.110,P<0.001);试验组粗大运动、个人与社会、手眼协调和总发育商均高于对照组(t>2.154,P<0.05);试验组身长大于对照组(t=2.027,P<0.05)。结论疏通矫正手法可促进cblC型MMA发育迟缓患儿神经心理发育和体格发育。

Objective To observe the effect of Dredging Correcting Manipulation on cblC methylmalonic aciduria(MMA).Methods From October,2017 to October,2018,72 children with cblC MMA combined with growth retardation were divided into control group(n=36)and experimental group(n=36)according to the consent of their parents.The control group accepted routine medicine,and the experimental group received Dredging Correcting Manipulation in addition.The Griffiths Development Scale-Chinese version(GDS-C)was used to evaluate the two groups before and after treatment.At the same time,body length,body mass and head circumference were measured.Results Six cases in the control group and five cases in the experimental group were dropped out.There was no significant difference in the development quotients of GDS-C in gross movement,personal and social,hearing and speech,hand-eye coordination,operation and total quotient between two groups before treatment(P>0.05).After treatment,all the development quotients increased in both groups(t>6.110,P<0.001),and the development quotients of GDS-C in gross movement,personal and social,hand-eye coordination and total quotient were higher in the experimental group than in the control group(t>2.154,P<0.05),as well as the body length(t=2.027,P<0.05).Conclusion Dredging Correcting Manipulation can promote the neuropsychological and physical development of children with cblC MMA combined with retardation.