对《KCNJ5体细胞突变与单侧原发性醛固酮增多症患者术后临床缓解有关》的短评

Brief comments on Somatic mutation of KCNJ5 is associated with hypertension remission after adrenalectomy in patients with unilateral primary aldosteronism

单侧原发性醛固酮增多症(PA)患者术后一般可获得完全生化缓解,但其中仅37%的患者术后可完全停止降压药物治疗(完全临床缓解),其原因尚不完全清楚[1]。最近Leticia A等在J Clin Endocrinol Metab撰文[Leticia A,et al.KCNJ5 somatic mutation is a predictor of hypertension remission after adrenalectomy for unilateral primary aldosteronism.J Clin Endocrinol Metab,2019,104(10):4695-4702]。该研究为一回顾性研究,旨在探讨单侧PA患者术后临床缓解的预测因子。基于最新的原发性醛固酮增多症手术结局(PASO)标准[1].