黑色素瘤免疫调节疫苗研发进展

Progress in Research and Development of Tumor Vaccine Immunotherapy for Melanoma

恶性黑色素瘤恶性度高,晚期患者预后不佳,免疫治疗是重要的辅助治疗方法,能够延长患者的生存期。随着新抗原概念的提出,肿瘤疫苗作为免疫治疗的新方法,已经引起各界的广泛关注。本文对恶性黑色素瘤免疫治疗中肿瘤疫苗的原理和研发进展进行综述。

Malignant melanomahas a high-grade malignancy and poor clinical prognosis.Immunotherapy is an important adjuvant treatment method that can prolong the survival of patients.With the proposal of the concept of neoantigen,tumor vaccine as a new method of immunotherapy has attracted wide attention.This article reviews the principles and development of Vaccine for Melanoma.