肺炎支原体肺炎患儿NLR、RDW的相关性分析

Correlation analysis of NLR and RDW in children with mycoplasma pneumonia

目的分析红细胞分布宽度(RDW)及中性粒细胞/淋巴细胞比值(NLR)在诊断肺炎支原体肺炎(MPP)中的临床意义,为早期识别重症肺炎支原体肺炎提供实验室证据。方法选取2019年2月~2019年8月诊断为肺炎支原体肺炎(MPP)的患儿65例作为MPP组(其中轻症组30例;重症组35例),健康儿童35例为对照组,患儿初次就诊时采末梢血,测定红细胞平均分布宽度(RDW)、中性粒细胞/淋巴细胞比值(NLR)水平,对结果进行统计学分析。结果①重症组及轻症组RDW分别为(14.350±0.540)%和(13.208±0.693)%,均高于对照组(11.505±0.769)%(P<0.05),且重症组RDW水平高于轻症组(P<0.05);重症组及轻症组NLR分别为(6.281±0.809)和(2.957±1.734),均高于对照组(1.804±0.309)(P<0.05),且重症组NLR水平高于轻症组(P<0.05);重症组及轻症组D-二聚体水平分别为(1300.391±310.760)mg/L和(310.252±60.480)mg/L,均高于对照组(180.640±25.840)mg/L(P<0.05),且重症组D-二聚体水平高于轻症组(P<0.05)。②支原体肺炎患儿RDW、NLR与D-二聚体呈显著正相关(P<0.01)。结论 RDW及NLR水平可作为诊断及评估病情较好的生物学指标。

Objective To analyze the clinical effect of red blood width(RDW) and neutrophil/lymphocyte ratio(NLR) in the diagnosis of mycoplasma pneumonia,in order to provide laboratory evidence for early diagnosis of severe mycoplasma pneumonia.Methods Sixty-five Children with mycoplasma pneumonia(MPP) in the Department of Pediatrics,Weifang People’s Hospital from February 2019 to August 2019 were selected as the MPP group(30 mild cases,35 severe cases).Thirty-five healthy children were selected as normal control group.The average red blood width(RDW) and neutrophil/lymphocyte ratio(NLR) were measured at the first visit,and the results were statistically analyzed.Results ①The levels of RDW in severe group[(14.350±0.540)%] and mild group[(13.208±0.693)%] were higher than those in control group[(11.505±0.769)%](P<0.05),and the levels of RDW in severe group were higher than those in mild group(P<0.05).The levels of NLR in severe group(6.281±0.809) and mild group(2.957±1.734) were higher than those in control group(1.804±0.309)(P<0.05),and the levels of NLR in severe group were higher than those in mild group(P<0.05).The levels of D-dimer in severe group[(1300.391±310.760)mg/L] and mild group[(310.252±60.480)mg/L] were higher than those in control group[(180.640±25.840)mg/L](P<0.05),the levels of D-dimer in severe group were higher than those in mild group(P<0.05).②The RDW and NLR level of children with mycoplasma pneumonia and were positively correlated with the D-dimer level.Conclusion The levels of RDW and NLR can be used as a good biological index for diagnosis and evaluation of the disease.