负压创面治疗技术在恶性黑素瘤腹股沟淋巴结清扫术中的应用价值

The Effect of Negative Pressure Wound Treatment in Inguinal Lymph Node Dissection for Malignant Melanoma

目的:探讨负压创面治疗技术在恶性黑素瘤腹股沟淋巴结清扫术中的应用价值。方法:回顾分析2002年1月-2018年12月就诊笔者医院整形外科并接受了腹股沟淋巴结清扫的恶性黑素瘤患者。纳入患者按照是否联合使用负压创面治疗技术,被分为负压创面治疗技术组和传统治疗组。对比两组患者的一般资料、术后愈合时间及并发症发生情况。结果:63例患者被纳入本研究,其中负压创面治疗技术组30例,传统治疗组33例。两组患者一般资料比较差异无统计学意义(P>0.05)。负压创面治疗技术组术后愈合时间明显短于传统治疗组,并且降低了感染(3.3%vs24.2%)、延迟愈合(16.7%vs42.4%)、皮下积液或血肿(3.3%vs30.3%)、淋巴漏(6.7%vs27.3%)的发生率,差异具有统计学意义(P<0.05)。结论:恶性黑素瘤腹股沟淋巴结清扫联合负压创面治疗技术,可以有效地缩短术后恢复时间,降低术后并发症发生率,值得临床上推广。

Objective To investigate the effect of negative pressure wound therapy(NPWT)in inguinal lymph node dissection(LND)in malignant melanoma(MM).Methods The patients with MM who received inguinal LND in our hospital were analyzed retrospectively,from January 2002 to December 2018.The enrolled patients were divided into the NPWT group and the traditional treatment group according to whether the NPWT was used.The general data,postoperative healing time and complications were compared between the two groups of patients.Results 63 patients were included in this study,including 30 patients in the NPWT group and 33 patients in the traditional treatment group.There was no significant difference in general data between the two groups(P>0.05).The healing time of the NPWT group was significantly shorter than that of the traditional treatment group,the difference was statistically significant(P<0.05).The incidence of infection(3.3%vs 24.2%),delayed healing(16.7%vs 42.4%),subcutaneous effusion or hematoma(3.3%vs 30.3%)and lymphatic leakage(6.7%vs 27.3%)in the NPWT group were lower than those in the control group((P<0.05).Conclusion The treatment of MM with inguinal LND combined with NPWT can effectively shorten the postoperative healing time and reduce the incidence of postoperative complications,so it is worth popularizing.