冠状动脉粥样硬化狭窄程度与肾功能的相关性

Correlation between the degree of coronary atherosclerotic stenosis and renal function

目的分析冠状动脉粥样硬化狭窄程度与肾功能的相关性。方法46例冠状动脉粥样硬化性心脏病患者(观察组)和44例冠状动脉粥样硬化患者(对照组)接受64层螺旋CT检查,评估冠状动脉狭窄程度,比较两组肾功能、FBG、LDL-C、HDL-C和TC等相关指标,分析其相关性。结果两组FBG、LDL-C、HDL-C和TC比较无统计学差异(P>0.05)。观察组BUN和SCr高于对照组(P<0.05);Pearson相关分析显示,观察组中冠状动脉狭窄程度评分与BUN和SCr呈正相关(r=0.638、0.763,P<0.01),对照组中尚未发现冠状动脉狭窄程度评分与BUN和SCr存在相关关系(r=0.037、0.080,P>0.05)。结论肾功能是冠状动脉粥样硬化狭窄程度的一个较好预测指标。

Objective To analyze the correlation between coronary atherosclerotic stenosis and renal function.Methods The 64-slice spiral CT examination was performed in 46 patients with coronary atherosclerotic heart disease(group A)and 44 patients with coronary atherosclerosis(group B),in whom the degree of coronary stenosis was evaluated.The BUN,SCr,FBG,LDL-C,HDL-C,TC and other relevant indicators were compared between the two groups.The correlation between BUN and SCr and the severity of coronary stenosis was analyzed.Results There were no statistical differences in FBG,LDL-C,HDL-C and TC between the two groups(P>0.05).The BUN and SCr in group A were higher than those in group B(P<0.05).Pearson correlation analysis showed that the degree of coronary artery stenosis was positively correlated with BUN and SCr in group A(r=0.638,0.763,P<0.01),which was not seen in group B(r=0.037,0.080,P>0.05).Conclusion Renal function is a good predictor of coronary atherosclerotic stenosis.