腹腔镜手术对良性卵巢肿瘤患者卵巢功能、免疫功能的影响

Effects of Laparoscopic Surgery on Ovarian Function and Immune Function in Patients with Benign Ovarian Tumors

目的对良性卵巢肿瘤患者采用腹腔镜手术治疗对其卵巢功能和免疫功能的影响进行探究。方法方便选择该院收治的良性肿瘤患者共计90例作为该次研究对象,选取时间段为2017年11月—2019年2月,按照随机数字表法将这些患者划分为常规组和微创组,每组45例。采用传统开腹手术对常规组患者予以治疗,采用腹腔镜手术对微创组患者予以治疗,在治疗结束后,对两组患者的卵巢功能和免疫功能进行观察和比较。结果常规组治疗前Ig G为(14.3±2.6)g/L,Ig A为(2.1±0.5)g/L,E2为(134.1±21.3)mmol/L,LH为(6.2±1.4)U/L,FSH为(11.3±1.4)U/L;微创组治疗前Ig G为(14.2±2.7)g/L,Ig A为(2.1±0.6)g/L,E2为(133.8±21.5)mmol/L,LH为(6.2±1.5)U/L,FSH为(11.4±1.3)U/L。常规组与微创组治疗前的免疫功能指标、卵巢功能指标比较差异无统计学意义(P>0.05)。常规组治疗后Ig G为(10.6±1.5)g/L,Ig A为(1.3±0.4)g/L,微创组治疗后的Ig G为(13.3±1.9)g/L,Ig A为(1.9±0.6)g/L。微创组治疗后免疫功能各项指标均明显优于常规组,差异有统计学意义(t=3.214、3.492,P<0.05)。常规组治疗后的E2为(116.7±12.2)mmol/L,LH为(9.2±1.1)U/L,FSH为(10.8±1.3)U/L,微创组治疗前的E2为(95.3±12.1)mmol/L,LH为(12.4±1.5)U/L,FSH为(8.4±1.1)U/L,微创组治疗后的卵巢功能各项指标均明显优于常规组,两组比较差异有统计学意义(t=3.855、3.627、3.391,P<0.05)。结论采用腹腔镜手术治疗良性卵巢肿瘤患者具有很好的效果,而且对患者的卵巢功能和免疫功能影响较小。

Objective To investigate the effect of laparoscopic surgery on the ovarian function and immune function of patients with benign ovarian tumors.Methods A total of 90 patients with benign tumors admitted to the hospital were convenient selected as the subjects of this study.The time period was from November 2017 to February 2019.These patients were divided into conventional and minimally invasive groups according to the random number table method There are 45 cases in each group.Conventional open surgery was used to treat patients in the conventional group,and laparoscopic surgery was used to treat patients in the minimally invasive group.After treatment,the ovarian and immune functions of the two groups were observed and compared.Results The beneral group before treatment,Ig G was(14.3±2.6)g/L,Ig A was(2.1±0.5)g/L,E2 was(134.1±21.3)mmol/L,and LH was(6.2±1.4)U/L,FSH was(11.3±1.4)U/L;the mininoally invasive group Ig G before treatment was(14.2±2.7)g/L,Ig A was(2.1±0.6)g/L,and E2 was(133.8±21.5)mmol/L,LH was(6.2±1.5)U/L,FSH was(11.4±1.3)U/L.There was no statistically significant difference between the routine group and the minimally invasive group before the treatment of immune function indexes and ovarian function indexes(P>0.05).The Ig G of the conventional group was(10.6±1.5)g/L,the Ig A was(1.3±0.4)g/L,the Ig G of the minimally invasive group was(13.3±1.9)g/L,and the Ig A was(1.9±0.6)g/L.After treatment,the immune function indexes of the minimally invasive group were significantly better than the conventional group,and the difference of two groups was statistically significant(t=3.214,3.492,P<0.05).E2 after treatment in the conventional group was(16.7±12.2)mmol/L,LH was(9.2±1.1)U/L,FSH was(10.8±1.3)U/L,and E2 in the minimally invasive group was(95.3±12.1)mmol/L,LH was(12.4±1.5)U/L,FSH was(8.4±1.1)U/L,the indexes of ovarian function after treatment in the minimally invasive group were significantly better than the conventional group,and the difference of two groups was statistically significant(t=3.855,3.627,3.391,P<0.05).Conclusion The use of laparoscopic surgery to treat patients with benign ovarian tumors has a good effect,and it has little effect on the ovarian function and immune function of patients.