盐酸米诺环素软膏结合碘仿纱条治疗干槽症的临床研究

Clinical study of minocycline hydrochloride and iodoform gauze in the treatment of dry socket

目的:研究并对比使用盐酸米诺环素软膏和碘仿纱条填塞拔牙窝治疗干槽症的效果。方法:收集2016年3月~2018年12月就诊于我科拔牙后干槽症患者133例,随机分为A、B、C组,A组(n=44)采用盐酸米诺环素软膏治疗,B组(n=44)采用碘仿纱条填塞拔牙窝治疗,C组(n=45)采用盐酸米诺环素软膏结合碘仿纱条填塞治疗。结果:显效率C组(80.0%)高于B组(61.4%)和A组(45.5%),差异有统计学意义(P<0.05);总有效率C组(100%)与B组(97.8%)比较差异无统计学意义(P>0.05),2组与A组(91.0%)比较差异均有统计学意义(P<0.05)。结论:干槽症治疗中,盐酸米诺环素软膏结合碘仿纱条填塞治疗效果良好,值得临床推广。

Objective:To study and compare the efficacy of minocycline hydrochloride ointment and iodoform gauze in the treatment of dry socket.Methods:A total of 133 patients with dry socket in our department from March 2016 to December 2018 were randomly divided into three groups:group A(n=44)treated with minocycline hydrochloride ointment,group B(n=44)treated with iodoform gauze filling socket,group C(n=45)treated with minocycline hydrochloride ointment and iodoform gauze filling.Results:Significantly effective rate in group C(80.0%)was higher than those of group B(61.4%)and group A(45.5%),with significant difference(both P<0.05).There was no significant difference in total effective rates between group C and group B(100% vs97.8%,P>0.05),but there was significant difference between group A(91.0%)and the other groups(P<0.05).Conclusion:In the treatment of dry socket,minocycline hydrochloride ointment combined with iodoform gauze tamponade is an ideal treatment method.